Literature DB >> 14698900

Structure and cross-reactivity of the O-antigen of Providencia stuartii O18 containing 3-acetamido-3,6-dideoxy-D-glucose.

Nina A Kocharova1, Aleksandra Błaszczyk, George V Zatonsky, Agnieszka Torzewska, Olga V Bystrova, Alexander S Shashkov, Yuriy A Knirel, Antoni Rozalski.   

Abstract

The O-polysaccharide (O-antigen) of Providencia stuartii O18 was obtained by mild acid degradation of the lipopolysaccharide and studied by chemical methods and NMR spectroscopy, including 2D 1H,1H COSY, TOCSY, NOESY and 1H,13C HSQC experiments. The following structure of the tetrasaccharide repeating unit of the polysaccharide was established: [structure: see text] where Qui3NAc is 3-acetamido-3,6-dideoxyglucose. Anti-P. stuartii O18 serum cross-reacted with the O-antigen of Proteus genomospecies 4, which could be accounted for the marked structural similarities of the main chain.

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Year:  2004        PMID: 14698900     DOI: 10.1016/j.carres.2003.10.022

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  3 in total

1.  The molecular architecture of QdtA, a sugar 3,4-ketoisomerase from Thermoanaerobacterium thermosaccharolyticum.

Authors:  James B Thoden; Hazel M Holden
Journal:  Protein Sci       Date:  2014-03-25       Impact factor: 6.725

2.  Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose.

Authors:  Andreas Pföstl; Sonja Zayni; Andreas Hofinger; Paul Kosma; Christina Schäffer; Paul Messner
Journal:  Biochem J       Date:  2008-02-15       Impact factor: 3.857

3.  Total synthesis of the O-antigen repeating unit of Providencia stuartii O49 serotype through linear and one-pot assemblies.

Authors:  Tanmoy Halder; Somnath Yadav
Journal:  Beilstein J Org Chem       Date:  2021-12-13       Impact factor: 2.883

  3 in total

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