Literature DB >> 14698894

Synthesis of (+)-(2R,3S,4R)-2,3,4-trihydroxycyclohexanone from D-glucose.

Ivone Carvalho1, Eduardo B de Melo.   

Abstract

We have described the synthesis of (+)-(2R,3S,4R)-2,3,4-trihydroxycyclohexanone by the reduction of a keto-conduritol derivative, the latter being prepared in five steps from (-)-(2S,3R,4S,5S)-2,3,4-tribenzyloxy-5-hydroxycyclohexanone, which is in turn readily synthesized from D-glucose.

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Year:  2004        PMID: 14698894     DOI: 10.1016/j.carres.2003.10.010

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  1 in total

1.  Homology modeling and molecular interaction field studies of alpha-glucosidases as a guide to structure-based design of novel proposed anti-HIV inhibitors.

Authors:  C H Tomich; P da Silva; Ivone Carvalho; C A Taft
Journal:  J Comput Aided Mol Des       Date:  2005-02       Impact factor: 3.686

  1 in total

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