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Literature DB >> 14698813

Advantages and disadvantages of Caenorhabditis elegans for aging research.

Abstract

The nematode Caenorhabditis elegans has been the organism of choice for most aging research, especially genetic approaches to aging. More than 70 longevity genes have been identified, with more to come, and these genes have been the subjects of intense study. I identify the major reasons for this and discuss limitations of this organism for future progress in research on aging.

Entities: Species

Mesh：

Year: 2003 PMID： 14698813 DOI： 10.1016/j.exger.2003.10.020

Source DB: PubMed Journal: Exp Gerontol ISSN： 0531-5565 Impact factor: 4.032

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Cited

22 in total

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Journal: Proc Natl Acad Sci U S A Date: 2010-10-25 Impact factor: 11.205

2. Genes that may modulate longevity in C. elegans in both dauer larvae and long-lived daf-2 adults.

Authors: Peter Ruzanov; Donald L Riddle; Marco A Marra; Sheldon J McKay; Steven M Jones
Journal: Exp Gerontol Date: 2007-04-21 Impact factor: 4.032

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Journal: Neurosci Bull Date: 2009-12 Impact factor: 5.203

Review 4. Revising the standard wisdom of C. elegans natural history: ecology of longevity.

Authors: E P Caswell-Chen; J Chen; E E Lewis; G W Douhan; S A Nadler; J R Carey
Journal: Sci Aging Knowledge Environ Date: 2005-10-05

Review 5. Fast photochemical oxidation of proteins (FPOP): A powerful mass spectrometry-based structural proteomics tool.

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Journal: J Biol Chem Date: 2019-07-01 Impact factor: 5.157

6. The ecology and biodemography of Caenorhabditis elegans.

Authors: J Chen; E E Lewis; J R Carey; Hal Caswell; E P Caswell-Chen
Journal: Exp Gerontol Date: 2006-09-11 Impact factor: 4.032

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