| Literature DB >> 14698184 |
Ahmed Kamal1, G Ramesh, O Srinivas, P Ramulu.
Abstract
Pyrene-linked pyrrolobenzodiazepine hybrids have been synthesized that exhibit potential anticancer activity in a number of human tumour cell lines. These hybrids also exhibit much enhanced DNA-binding ability in comparison to the parent pyrrolobenzodiazepine ring system (DC-81).Entities:
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Year: 2004 PMID： 14698184 DOI： 10.1016/j.bmcl.2003.10.050
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823