| Literature DB >> 14698175 |
Alcides J M da Silva1, Antonio L Coelho, Alessandro B C Simas, Raphael A M Moraes, Diogo A Pinheiro, Fabrício F A Fernandes, Emerson Z Arruda, Paulo R R Costa, Paulo A Melo.
Abstract
Edunol (3), a pterocarpan isolated from Harpalyce brasiliana, a plant used in the northeast of Brazil against snakebites, was obtained by synthesis and showed antimyotoxic, antiproteolytic and PLA2 inhibitor properties. These proprieties could be improved through the synthesis of a bioisoster (5), where the prenyl group was replaced by the benzyl group.Entities:
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Year: 2004 PMID： 14698175 DOI： 10.1016/j.bmcl.2003.10.044
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823