| Literature DB >> 14698150 |
Alberto Coelho1, Eddy Sotelo, Nuria Fraiz, Matilde Yáñez, Reyes Laguna, Ernesto Cano, Enrique Raviña.
Abstract
A convenient and efficient palladium-catalysed retro-ene-assisted method has been developed to prepare a series of 5-substituted-6-phenyl-3(2H)-pyridazinones as potential antiplatelet drugs. The most active compounds were those that contain a 3-phenyl-3-oxo-propenyl fragment or a phenylthio group at position 5 of the heterocyclic ring.Entities:
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Year: 2004 PMID： 14698150 DOI： 10.1016/j.bmcl.2003.11.009
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823