| Literature DB >> 14697520 |
María A Navarro1, Sergio Acín, María Iturralde, Lucía Calleja, Ricardo Carnicer, Mario A Guzmán-García, Nieves González-Ramón, Pedro Mata, Beatriz Isabel, Clemente J López-Bote, Fermín Lampreave, Andrés Piñeiro, Jesús Osada.
Abstract
Pig apolipoprotein (apo) A-IV cDNA was cloned, characterized and compared to the human ortholog. Mature porcine apo A-IV consists of 362 amino acids and displays a 75.6% sequence identity with human protein. Pig apo A-IV is the smallest reported mammalian apo A-IV because it lacks the repeated motifs of glutamine and glutamic acid at the carboxyl terminus. A phylogenic tree of apo A-IV mammalian proteins reveals that porcine apo A-IV is more closely related to humans and primates than to rodents. This protein is highly hydrophobic and is mainly associated with lipoproteins.Entities:
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Year: 2004 PMID： 14697520 DOI： 10.1016/j.gene.2003.10.007
Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688