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Literature DB >> 14697350

Cell migration: Rho GTPases lead the way.

Abstract

Rho GTPases control signal transduction pathways that link cell surface receptors to a variety of intracellular responses. They are best known as regulators of the actin cytoskeleton, but in addition they control cell polarity, gene expression, microtubule dynamics and vesicular trafficking. Through these diverse functions, Rho GTPases influence many aspects of cell behavior. This review will focus specifically on their role in cell migration.

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Year: 2004 PMID： 14697350 DOI： 10.1016/j.ydbio.2003.06.003

Source DB: PubMed Journal: Dev Biol ISSN： 0012-1606 Impact factor: 3.582

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Cited

552 in total

1. Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells.

Authors: Ryota Itoh; Shigenori Miura; Aki Takimoto; Shunya Kondo; Hiroko Sano; Yuji Hiraki
Journal: J Bone Miner Metab Date: 2010-05-11 Impact factor: 2.626

2. Molecular recognition of leucine-aspartate repeat (LD) motifs by the focal adhesion targeting homology domain of cerebral cavernous malformation 3 (CCM3).

Authors: Xiaofeng Li; Weidong Ji; Rong Zhang; Ewa Folta-Stogniew; Wang Min; Titus J Boggon
Journal: J Biol Chem Date: 2011-06-01 Impact factor: 5.157

3. High-throughput flow cytometry bead-based multiplex assay for identification of Rho GTPase inhibitors.

Authors: Zurab Surviladze; Susan M Young; Larry A Sklar
Journal: Methods Mol Biol Date: 2012

4. Induction of GM1a/GD1b synthase triggers complex ganglioside expression and alters neuroblastoma cell behavior; a new tumor cell model of ganglioside function.

Authors: Lixian Dong; Yihui Liu; Anamaris M Colberg-Poley; Karen Kaucic; Stephan Ladisch
Journal: Glycoconj J Date: 2011-04-26 Impact factor: 2.916

Cell migration: Rho GTPases lead the way.

1. Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells.

2. Molecular recognition of leucine-aspartate repeat (LD) motifs by the focal adhesion targeting homology domain of cerebral cavernous malformation 3 (CCM3).

3. High-throughput flow cytometry bead-based multiplex assay for identification of Rho GTPase inhibitors.

4. Induction of GM1a/GD1b synthase triggers complex ganglioside expression and alters neuroblastoma cell behavior; a new tumor cell model of ganglioside function.

5. Rac regulation of chemotaxis and morphogenesis in Dictyostelium.

6. Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia.

7. Cell motility: The necessity of Rac1 GDP/GTP flux.

8. New slbo-Gal4 driver lines for the analysis of border cell migration during Drosophila oogenesis.

9. LIM domain only 2 induces glioma invasion via cytosolic p27(KIP1).

10. Small GTPase RhoE/Rnd3 is a critical regulator of Notch1 signaling.