| Literature DB >> 14695814 |
Antonio H Daranas1, José J Fernández, Ezequiel Q Morales, Manuel Norte, José A Gavín.
Abstract
Okadaic acid (OA) is a toxin responsible for diarrhetic shellfish poisoning and is an extremely useful tool for studying processes that are regulated by phosphorylation, although the exact mechanism of action is still undetermined. We report on a study that proved the existence of OA in an unusual dimeric form when complexed with potassium ion. The proposed structure of this dimer is based on spectroscopic and conformational studies.Entities:
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Year: 2004 PMID： 14695814 DOI： 10.1021/jm034189b
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446