Literature DB >> 14695808

Discorhabdins S, T, and U, new cytotoxic pyrroloiminoquinones from a deep-water Caribbean sponge of the genus Batzella.

Sarath P Gunasekera1, Ignacio A Zuleta, Ross E Longley, Amy E Wright, Shirley A Pomponi.   

Abstract

Discorhabdins S, T, and U (1-3), three new discorhabdin analogues, have been isolated from a deep-water marine sponge of the genus Batzella. These discorhabdin analogues showed in vitro cytotoxicity against PANC-1, P-388, and A-549 cell lines. The isolation and structure elucidation of discorhabdins S, T, and U are described.

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Year:  2003        PMID： 14695808     DOI： 10.1021/np030292s

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  15 in total

1.  Neopetrosiquinones A and B, sesquiterpene benzoquinones isolated from the deep-water sponge Neopetrosia cf. proxima.

Authors:  Priscilla L Winder; Heather L Baker; Patricia Linley; Esther A Guzmán; Shirley A Pomponi; M Cristina Diaz; John K Reed; Amy E Wright
Journal:  Bioorg Med Chem       Date:  2011-09-21       Impact factor: 3.641

2.  Analogues of the Potent Antitumor Compound Leiodermatolide from a Deep-Water Sponge of the Genus Leiodermatium.

Authors:  Amy E Wright; Jill C Roberts; Esther A Guzmán; Tara P Pitts; Shirley A Pomponi; John K Reed
Journal:  J Nat Prod       Date:  2017-01-30       Impact factor: 4.050

3.  Total synthesis of zyzzyanones A-D.

Authors:  Dwayaja H Nadkarni; Srinivasan Murugesan; Sadanandan E Velu
Journal:  Tetrahedron       Date:  2013-05-20       Impact factor: 2.457

4.  A facile synthesis of bispyrroloquinone and bispyrroloiminoquinone ring system of marine alkaloids.

Authors:  Srinivasan Murugesan; Dwayaja H Nadkarni; Sadanandan E Velu
Journal:  Tetrahedron Lett       Date:  2009-06-24       Impact factor: 2.415

5.  Gymnochromes E and F, cytotoxic phenanthroperylenequinones from a deep-water crinoid, Holopus rangii.

Authors:  Hilaire V Kemami Wangun; Alexander Wood; Catherine Fiorilla; John K Reed; Peter J McCarthy; Amy E Wright
Journal:  J Nat Prod       Date:  2010-04-23       Impact factor: 4.050

Review 6.  Synthesis of the marine pyrroloiminoquinone alkaloids, discorhabdins.

Authors:  Yasufumi Wada; Hiromichi Fujioka; Yasuyuki Kita
Journal:  Mar Drugs       Date:  2010-04-21       Impact factor: 5.118

Review 7.  Recent advances in isolation, synthesis, and evaluation of bioactivities of bispyrroloquinone alkaloids of marine origin.

Authors:  Bhavitavya Nijampatnam; Shilpa Dutta; Sadanandan E Velu
Journal:  Chin J Nat Med       Date:  2015-08

8.  Analogs of the marine alkaloid makaluvamines: synthesis, topoisomerase II inhibition, and anticancer activity.

Authors:  Bidhan A Shinkre; Kevin P Raisch; Liming Fan; Sadanandan E Velu
Journal:  Bioorg Med Chem Lett       Date:  2007-02-25       Impact factor: 2.823

9.  Evidence of a putative deep sea specific microbiome in marine sponges.

Authors:  Jonathan Kennedy; Burkhardt Flemer; Stephen A Jackson; John P Morrissey; Fergal O'Gara; Ferghal O'Gara; Alan D W Dobson
Journal:  PLoS One       Date:  2014-03-26       Impact factor: 3.240

10.  Indolo[3,2-a]carbazoles from a deep-water sponge of the genus Asteropus.

Authors:  Floyd Russell; Dedra Harmody; Peter J McCarthy; Shirley A Pomponi; Amy E Wright
Journal:  J Nat Prod       Date:  2013-09-24       Impact factor: 4.050
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