| Literature DB >> 1469431 |
L Austin1, J Bower, J Kurek, N Vakakis.
Abstract
It has been shown previously that leukaemia inhibitory factor (LIF) and transforming growth factor-alpha (TGF-alpha) stimulate proliferation of primary cultures of murine myoblasts. We now show that human myoblasts respond in a similar manner to LIF and TGF-alpha. These responses occur over a range of growth conditions. There are total additive effects in both human and murine myoblasts between LIF and TGF-alpha and LIF and fibroblast growth factor-beta (FGF-beta), but not between LIF and interleukin-6 (IL-6) or insulin-like growth factor 1 (IGF-1). The LIF response is initiated by a short exposure to the cytokine and is maintained for prolonged periods in its absence.Entities:
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Year: 1992 PMID： 1469431 DOI： 10.1016/0022-510x(92)90149-f
Source DB: PubMed Journal: J Neurol Sci ISSN： 0022-510X Impact factor: 3.181