Literature DB >> 14694058

Chronic neuropathy with IgM anti-ganglioside antibodies: lack of long term response to rituximab.

R Rojas-García1, E Gallardo, I de Andrés, N de Luna, C Juarez, P Sánchez, I Illa.   

Abstract

Two patients with chronic motor neuropathy, high antiganglioside antibody (AGA) titers, and a declining response to IV immunoglobulins were treated with rituximab at a standard dose. The drug was well tolerated and effectively eliminated peripheral B cells (CD20+), but AGA titers continued significantly high. No clinical improvement was detected during the 1-year follow-up.

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Year:  2003        PMID: 14694058     DOI: 10.1212/01.wnl.0000098996.02934.86

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  14 in total

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Authors:  Lotte Vlam; W-Ludo van der Pol; Elisabeth A Cats; Dirk C Straver; Sanneke Piepers; Hessel Franssen; Leonard H van den Berg
Journal:  Nat Rev Neurol       Date:  2011-11-22       Impact factor: 42.937

2.  Pathogenesis and treatment of immune-mediated neuropathies.

Authors:  Helmar C Lehmann; Gerd Meyer Zu Horste; Bernd C Kieseier; Hans-Peter Hartung
Journal:  Ther Adv Neurol Disord       Date:  2009-07       Impact factor: 6.570

3.  Guillain-Barre syndrome in a patient with diffuse large B-cell lymphoma, and rituximab maintenance therapy. An association beyond anecdotal evidence?

Authors:  Alberto Carmona; Juan Domingo Alonso; Manuel de las Heras; Agustín Navarrete
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Review 4.  Multifocal motor neuropathy: current therapies and novel strategies.

Authors:  Eduardo Nobile-Orazio; Francesca Gallia
Journal:  Drugs       Date:  2013-04       Impact factor: 9.546

Review 5.  Immunotherapy for IgM anti-myelin-associated glycoprotein paraprotein-associated peripheral neuropathies.

Authors:  Michael Pt Lunn; Eduardo Nobile-Orazio
Journal:  Cochrane Database Syst Rev       Date:  2016-10-04

Review 6.  Treatment of dys-immune neuropathies.

Authors:  Eduardo Nobile-Orazio
Journal:  J Neurol       Date:  2005-04       Impact factor: 4.849

Review 7.  IVIg in idiopathic autoimmune neuropathies: analysis in the light of the latest results.

Authors:  Eduardo Nobile-Orazio; Fabrizia Terenghi
Journal:  J Neurol       Date:  2005-05       Impact factor: 4.849

8.  Is there a role for rituximab in the treatment of idiopathic childhood nephrotic syndrome?

Authors:  Graham C Smith
Journal:  Pediatr Nephrol       Date:  2007-02-20       Impact factor: 3.714

9.  Chronic ataxic neuropathy mimicking dorsal midbrain syndrome.

Authors:  S D Arbogast; S Khanna; D W Koontz; R L Tomsak; B Katirji; R J Leigh
Journal:  J Neurol Neurosurg Psychiatry       Date:  2007-05-15       Impact factor: 10.154

Review 10.  Immunosuppressant and immunomodulatory treatments for multifocal motor neuropathy.

Authors:  T Umapathi; Richard A C Hughes; Eduardo Nobile-Orazio; Jean-Marc Léger
Journal:  Cochrane Database Syst Rev       Date:  2015-03-04
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