| Literature DB >> 14693842 |
G Cole, N Coleman, E Soilleux.
Abstract
The process by which hepatitis C virus (HCV) enters cells and the reason for its hepatotropism remain obscure. Recently, the human immunodeficiency virus (HIV) binding lectins, DC-SIGN and DC-SIGNR, were shown to bind HCV. This article reports the expression of DC-SIGN and DC-SIGNR in HCV related liver disease and discusses whether these lectins, in particular DC-SIGNR, are responsible for HCV hepatotropism.Entities:
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Year: 2004 PMID: 14693842 PMCID: PMC1770186 DOI: 10.1136/jcp.57.1.79
Source DB: PubMed Journal: J Clin Pathol ISSN: 0021-9746 Impact factor: 3.411