Literature DB >> 14693567

Sequencing of Neisseria meningitidis penA gene: the key to success in defining penicillin G breakpoints.

Luisa Arreaza1, Celia Salcedo, Belén Alcalá, María José Uría, Raquel Abad, Rocío Enríquez, Julio A Vázquez.   

Abstract

Testing of susceptibility to penicillin G by E-test and sequencing of an internal fragment of the penA gene were done for 43 meningococcal strains. Those strains for which the MIC was >/=0.094 micro g/ml showed mosaic alleles, so 0.094 micro g/ml is suggested as the penicillin G intermediate breakpoint when E-test is used.

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Year:  2004        PMID： 14693567      PMCID： PMC310191          DOI： 10.1128/AAC.48.1.358-359.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  Antimicrobial resistance of Neisseria meningitidis in the United States, 1997. The Active Bacterial Core Surveillance (ABCs) Team.

Authors:  N E Rosenstein; S A Stocker; T Popovic; F C Tenover; B A Perkins
Journal:  Clin Infect Dis       Date:  2000-01       Impact factor: 9.079

2.  Role of interspecies transfer of chromosomal genes in the evolution of penicillin resistance in pathogenic and commensal Neisseria species.

Authors:  B G Spratt; L D Bowler; Q Y Zhang; J Zhou; J M Smith
Journal:  J Mol Evol       Date:  1992-02       Impact factor: 2.395

3.  Antibiotic susceptibility testing.

Authors:  C Block
Journal:  Methods Mol Med       Date:  2001

4.  Antibiotic susceptibility patterns of Neisseria meningitidis isolates from patients and asymptomatic carriers.

Authors:  L Arreaza; L de La Fuente; J A Vázquez
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

5.  Molecular Approach for the Study of Penicillin Resistance In Neisseria meningitidis.

Authors:  L Arreaza; J A Vázquez
Journal:  Methods Mol Med       Date:  2001
  5 in total
  6 in total

1.  Combined real-time PCR and pyrosequencing strategy for objective, sensitive, specific, and high-throughput identification of reduced susceptibility to penicillins in Neisseria meningitidis.

Authors:  Sara Thulin; Per Olcén; Hans Fredlund; Magnus Unemo
Journal:  Antimicrob Agents Chemother       Date:  2007-12-10       Impact factor: 5.191

2.  Evolutionary changes in antimicrobial resistance of invasive Neisseria meningitidis isolates in Belgium from 2000 to 2010: increasing prevalence of penicillin nonsusceptibility.

Authors:  Sophie Bertrand; Françoise Carion; René Wintjens; Vanessa Mathys; Raymond Vanhoof
Journal:  Antimicrob Agents Chemother       Date:  2012-01-30       Impact factor: 5.191

3.  Neisseria meningitidis C:2b:P1.2,5 with decreased susceptibility to penicillin isolated from a patient with meningitis and purpura fulminans.

Authors:  P Fangio; L Desbouchages; J C Lachérade; B De Jonghe; J P Terville; M Leneveu; H Outin
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2005-02       Impact factor: 3.267

4.  Total variation in the penA gene of Neisseria meningitidis: correlation between susceptibility to beta-lactam antibiotics and penA gene heterogeneity.

Authors:  Sara Thulin; Per Olcén; Hans Fredlund; Magnus Unemo
Journal:  Antimicrob Agents Chemother       Date:  2006-10       Impact factor: 5.191

5.  Target gene sequencing to characterize the penicillin G susceptibility of Neisseria meningitidis.

Authors:  Muhamed-Kheir Taha; Julio A Vázquez; Eva Hong; Desiree E Bennett; Sophie Bertrand; Suzana Bukovski; Mary T Cafferkey; Françoise Carion; Jens Jørgen Christensen; Mathew Diggle; Giles Edwards; Rocío Enríquez; Cecilia Fazio; Matthias Frosch; Sigrid Heuberger; Steen Hoffmann; Keith A Jolley; Marcin Kadlubowski; Amel Kechrid; Konstantinos Kesanopoulos; Paula Kriz; Lotte Lambertsen; Ileanna Levenet; Martin Musilek; Metka Paragi; Aouatef Saguer; Anna Skoczynska; Paola Stefanelli; Sara Thulin; Georgina Tzanakaki; Magnus Unemo; Ulrich Vogel; Maria Leticia Zarantonelli
Journal:  Antimicrob Agents Chemother       Date:  2007-05-21       Impact factor: 5.191

6.  Neisseria meningitidis intermediately resistant to penicillin and causing invasive disease in South Africa in 2001 to 2005.

Authors:  Mignon du Plessis; Anne von Gottberg; Cheryl Cohen; Linda de Gouveia; Keith P Klugman
Journal:  J Clin Microbiol       Date:  2008-07-23       Impact factor: 5.948
  6 in total

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