Literature DB >> 14693228

Bioactive flavonoids from Kaempferia parviflora.

Chavi Yenjai1, Khanchara Prasanphen, Supawadee Daodee, Varima Wongpanich, Prasat Kittakoop.   

Abstract

Nine flavonoids (1-9) have been isolated from Kaempferia parviflora. Among these, 5,7,4'-trimethoxyflavone (8) and 5,7,3',4'-tetramethoxyflavone (9) exhibited antiplasmodial activity against Plasmodium falciparum, with IC50 values of 3.70 and 4.06 microg/ml, respectively. 3,5,7,4'-Tetramethoxyflavone (7) and compound 8 possessed antifungal activity against Candida albicans with respective IC50 values of 39.71 and 17.63 microg/ml, and also showed mild antimycobacterial activity with the minimum inhibitory concentrations (MIC) of 200 and 50 microg/ml, respectively. However, none of the isolated compounds demonstrated cytotoxicity against KB, BC and NCI-H187 cell lines.

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Year:  2004        PMID： 14693228     DOI： 10.1016/j.fitote.2003.08.017

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  33 in total

1.  Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones.

Authors:  Thomas Walle; Nga Ta; Toshihiko Kawamori; Xia Wen; Petra A Tsuji; U Kristina Walle
Journal:  Biochem Pharmacol       Date:  2006-12-28       Impact factor: 5.858

2.  Kaempferia parviflora, a plant used in traditional medicine to enhance sexual performance contains large amounts of low affinity PDE5 inhibitors.

Authors:  Prapapan Temkitthawon; Thomas R Hinds; Joseph A Beavo; Jarupa Viyoch; Khanit Suwanborirux; Wittaya Pongamornkul; Pattara Sawasdee; Kornkanok Ingkaninan
Journal:  J Ethnopharmacol       Date:  2011-08-30       Impact factor: 4.360

3.  Antiobesity effects of Kaempferia parviflora in spontaneously obese type II diabetic mice.

Authors:  Tomoko Akase; Tsutomu Shimada; Susumu Terabayashi; Yukinobu Ikeya; Hiromi Sanada; Masaki Aburada
Journal:  J Nat Med       Date:  2010-09-03       Impact factor: 2.343

4.  New flav-3-en-3-ol glycosides, kaempferiaosides C and D, and acetophenone glycosides, kaempferiaosides E and F, from the rhizomes of Kaempferia parviflora.

Authors:  Saowanee Chaipech; Toshio Morikawa; Kiyofumi Ninomiya; Masayuki Yoshikawa; Yutana Pongpiriyadacha; Takao Hayakawa; Osamu Muraoka
Journal:  J Nat Med       Date:  2011-11-20       Impact factor: 2.343

5.  Transdermal permeation of Kaempferia parviflora methoxyflavones from isopropyl myristate-based vehicles.

Authors:  Sarunya Tuntiyasawasdikul; Ekapol Limpongsa; Napaphak Jaipakdee; Bungorn Sripanidkulchai
Journal:  AAPS PharmSciTech       Date:  2014-05-03       Impact factor: 3.246

6.  Effects of ethyl acetate extract of Kaempferia parviflora on brown adipose tissue.

Authors:  Hiroko Kobayashi; Emi Horiguchi-Babamoto; Mio Suzuki; Hiroko Makihara; Hiroshi Tomozawa; Masahito Tsubata; Tsutomu Shimada; Kiyoshi Sugiyama; Masaki Aburada
Journal:  J Nat Med       Date:  2015-09-19       Impact factor: 2.343

Review 7.  Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?

Authors:  Thomas Walle
Journal:  Semin Cancer Biol       Date:  2007-05-13       Impact factor: 15.707

8.  Anti-proliferative and apoptotic activities of constituents of chloroform extract of Juglans regia leaves.

Authors:  M Salimi; M H Ardestaniyan; H Mostafapour Kandelous; S Saeidnia; A R Gohari; A Amanzadeh; H Sanati; Z Sepahdar; S Ghorbani; M Salimi
Journal:  Cell Prolif       Date:  2014-01-27       Impact factor: 6.831

9.  Increased vascular eNOS and cystathionine-γ-lyase protein after 6 weeks oral administration of 3, 5, 7, 3', 4'-pentamethoxyflavone to middle-aged male rats.

Authors:  Somruedee Yorsin; Kanyanatt Kanokwiroon; Nisaudah Radenahmad; Chaweewan Jansakul
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2016-07-28       Impact factor: 3.000

Review 10.  Methylation of dietary flavones increases their metabolic stability and chemopreventive effects.

Authors:  Thomas Walle
Journal:  Int J Mol Sci       Date:  2009-11-18       Impact factor: 6.208
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