Literature DB >> 14693219

Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora.

Hyun Ok Yang1, Woo Kyung Ko, Jae Youn Kim, Hwan Seong Ro.   

Abstract

Paeoniflorin (1), isolated from the methanol extract of Paeonia lactiflora, showed a lowering effect on cholesterol level in the experimentally-induced hyperlipidemic rats. Paeoniflorin showed a significantly lowering effect of total cholesterol, LDL and triglyceride levels compared with the control group at the dose of 200 and 400 mg/kg, p.o. once a day for 4 weeks.

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Year:  2004        PMID： 14693219     DOI： 10.1016/j.fitote.2003.08.016

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  12 in total

1.  Paeoniflorin attenuates pressure overload-induced cardiac remodeling via inhibition of TGFβ/Smads and NF-κB pathways.

Authors:  Heng Zhou; He-Xin Yang; Yuan Yuan; Wei Deng; Jie-Yu Zhang; Zhou-Yan Bian; Jing Zong; Jia Dai; Qi-Zhu Tang
Journal:  J Mol Histol       Date:  2013-02-17       Impact factor: 2.611

2.  Coupling the high-resolution LC-MS characterisation of the phenolic compounds with the antimicrobial and antibiofilm properties of helencha (Enydra fluctuans Lour.).

Authors:  Tanmay Kumar Koley; Zareen Khan; Dasharath Oulkar; Tuhina Banerjee; Aradhana Singh; Suhas Gorakh Karkute; Kaushik Banerjee
Journal:  J Food Sci Technol       Date:  2021-01-17       Impact factor: 2.701

3.  Protective effect of paeoniflorin against optic nerve crush.

Authors:  Jing Li; Xinchun Xiong; Yunhai Liu
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2007-12

4.  Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway.

Authors:  Yi-Fei Liu; Lei Zhang; Qi Wu; Lin-Yin Feng
Journal:  Acta Pharmacol Sin       Date:  2021-05-11       Impact factor: 6.150

5.  A 12-week, randomized, double-blind, placebo-controlled study assessing the efficacy of EGHB010, a standardized extract of Paeoniae radix and Glycyrrhizae radix, in patients with early age-related macular degeneration.

Authors:  Joo Young Kim; Mirinae Kim; Rae Young Kim; Woo Kyung Park; Young-Hoon Park
Journal:  Ann Transl Med       Date:  2021-04

6.  Evaluation of the In Vivo Therapeutic Effects of Radix Paeoniae Rubra Ethanol Extract with the Hypoglycemic Activities Measured from Multiple Cell-Based Assays.

Authors:  Chia-Chuan Chang; Wei Yuan; Yun-Lian Lin; Ren-Shyan Liu; Yi-Chen Juan; Wan-Hua Sun; Huey Jen Tsay; Hsiu-Chen Huang; Yu-Ching Lee; Hui-Kang Liu
Journal:  Evid Based Complement Alternat Med       Date:  2016-11-29       Impact factor: 2.629

7.  Effects of an Enriched Extract of Paeoniflorin, a Monoterpene Glycoside used in Chinese Herbal Medicine, on Cholesterol Metabolism in a Hyperlipidemic Rat Model.

Authors:  Huiming Hu; Qiaoqiao Zhu; Jie Su; Yajun Wu; Yanchen Zhu; Yin Wang; Hui Fang; Minxia Pang; Bo Li; Suhong Chen; Guiyuan Lv
Journal:  Med Sci Monit       Date:  2017-07-14

8.  Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats.

Authors:  Zhihong Ma; Li Chu; Hongying Liu; Weijie Wang; Jieru Li; Wenzao Yao; Jianfeng Yi; Yue Gao
Journal:  Sci Rep       Date:  2017-03-16       Impact factor: 4.379

9.  Characterization of the Therapeutic Profile of Albiflorin for the Metabolic Syndrome.

Authors:  Xiu Zhou; Sherouk Fouda; Xiao-Yi Zeng; Dongli Li; Kun Zhang; Jun Xu; Ji-Ming Ye
Journal:  Front Pharmacol       Date:  2019-10-11       Impact factor: 5.810

10.  Evaluation of Effects of Chinese Prescription Kangen-karyu on Diabetes-Induced Alterations such as Oxidative Stress and Apoptosis in the Liver of Type 2 Diabetic db/db Mice.

Authors:  Chan Hum Park; Jeong Sook Noh; Takuya Okamoto; Jong Cheol Park; Takako Yokozawa
Journal:  Evid Based Complement Alternat Med       Date:  2012-08-30       Impact factor: 2.629
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