Literature DB >> 14692696

The molecular era of myology.

George Karpati1, Michael Sinnreich.   

Abstract

This review covers, in general terms, the salient features and impact of molecular myology under the following headings: its role in providing clues for the understanding of molecular etiology and pathogenesis of genetic myopathies, its contribution to the modernization and rationalization of the classification of muscle diseases, providing means of precise diagnosis and prevention of myopathies, development of radically new cell and gene therapies, and determination of future research directions. Myology appears to be among the medical disciplines that have benefited a great deal from molecular science. This remarkable progress will hopefully translate into effective treatment capabilities in the near future.

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Year:  2003        PMID: 14692696     DOI: 10.1093/jnen/62.12.1203

Source DB:  PubMed          Journal:  J Neuropathol Exp Neurol        ISSN: 0022-3069            Impact factor:   3.685


  2 in total

1.  Inducible overexpression of wild-type prion protein in the muscles leads to a primary myopathy in transgenic mice.

Authors:  Shenghai Huang; Jingjing Liang; Mengjie Zheng; Xinyi Li; Meiling Wang; Ping Wang; Difernando Vanegas; Di Wu; Bikram Chakraborty; Arthur P Hays; Ken Chen; Shu G Chen; Stephanie Booth; Mark Cohen; Pierluigi Gambetti; Qingzhong Kong
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-09       Impact factor: 11.205

2.  Muscle biopsies in children--an evaluation of histopathology and clinical value during a 5-year period.

Authors:  Marius Kurås Skram; Sasha Gulati; Erik Larsson; Sigurd Lindal; Sverre Helge Torp
Journal:  Ups J Med Sci       Date:  2009       Impact factor: 2.384

  2 in total

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