Literature DB >> 14692205

The technology behind Colgate Total Advanced Fresh.

Malcolm I Williams1, Diane Cummins.   

Abstract

In the early 1990s, a breakthrough toothpaste, Colgate Total, was launched with documented long-lasting activity against plaque, gingivitis, calculus, tooth decay, and bad breath. The technology behind this toothpaste is the combination of triclosan, a polyvinylmethylether/maleic acid copolymer, and sodium fluoride. The copolymer ensures maximal oral retention and subsequent release of the antibacterial triclosan. Effective levels of triclosan have been observed in the oral cavity 12 hours after brushing the teeth, allowing prolonged control of oral bacteria that may cause the most common dental problems, including bad breath. Similarly, the enhanced retention of triclosan to oral surfaces after using this revolutionary toothpaste for up to 2 years has led to significantly reduced incremental coronal caries compared to an American Dental Association-Approved anticavity fluoride toothpaste. Furthermore, significantly less calcium remained in dental plaque after brushing the teeth with the triclosan/copolymer toothpaste, resulting in the formation of less tartar. In keeping with the multiple oral health benefits provided by Colgate Total, consumers are now offered a new dentifrice, Colgate Total Advanced Fresh, which provides the numerous therapeutic and esthetic benefits that are the hallmark of Colgate Total. The new dentifrice, which contains an impactful breath-freshening flavor, has been documented to provide sustained control of bad breath over 12 hours.

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Year:  2003        PMID: 14692205

Source DB:  PubMed          Journal:  Compend Contin Educ Dent        ISSN: 1548-8578


  3 in total

1.  Clinical efficacy of a specifically targeted antimicrobial peptide mouth rinse: targeted elimination of Streptococcus mutans and prevention of demineralization.

Authors:  R Sullivan; P Santarpia; S Lavender; E Gittins; Z Liu; M H Anderson; J He; W Shi; R Eckert
Journal:  Caries Res       Date:  2011-08-19       Impact factor: 4.056

2.  Targeted Antimicrobial Peptides: A Novel Technology to Eradicate Harmful Streptococcus Mutans.

Authors:  Lihong Guo; Anna Edlund
Journal:  J Calif Dent Assoc       Date:  2017-10

3.  The Effect of Toothpastes Containing Natural Extracts on Bacterial Species of a Microcosm Biofilm and on Enamel Caries Development.

Authors:  Aline Silva Braga; Mohamed Mostafa Hefny Abdelbary; Rafaela Ricci Kim; Fernanda Pereira de Souza Rosa de Melo; Luiz Leonardo Saldanha; Anne Lígia Dokkedal; Georg Conrads; Marcella Esteves-Oliveira; Ana Carolina Magalhães
Journal:  Antibiotics (Basel)       Date:  2022-03-19
  3 in total

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