Literature DB >> 14691429

Cost of care distribution in atrial fibrillation patients: the COCAF study.

Jean-Yves Le Heuzey1, Olivier Paziaud, Olivier Piot, Mina Ait Said, Xavier Copie, Thomas Lavergne, Louis Guize.   

Abstract

BACKGROUND: Atrial fibrillation (AF) currently represents a major economic burden for society. Very few studies have been performed to evaluate the cost of care for AF patients. This study is a large prospective survey designed to analyze the different cost drivers in the treatment of these patients. This survey, named Cost of Care in Atrial Fibrillation (COCAF), evaluated the cost of care for patients with AF treated by cardiologists in general office practice.
METHODS: A group of 671 patients was recruited by 82 cardiologists distributed in all regions of France. The mean age of the patients was 69 years, and 64% were male. The mean follow-up was 329 +/- 120 days. The costs of care were analyzed from the health care payer and the societal perspectives.
RESULTS: During the follow-up period, 21 patients (3.13%) died and 210 (31.3%) patients were hospitalized. The number of hospitalizations and deaths was significantly higher in the group of persistent or permanent AF (PEAF) patients, as compared to paroxysmal AF (PAAF) patients. Hospitalizations were much more frequent in the PEAF group (127) than in the PAAF group (83, P <.05). Deaths were also much more frequent in the PEAF group (17) as compared to the PAAF group (4, P <.001). From the societal perspective, the first cost driver was hospitalizations (52%), followed by drugs (23%), consultations (9%), further investigations (8%), loss of work (6%), and paramedical procedures (2%). In multivariate analysis the following parameters were significantly associated with higher costs: heart failure (P <.04), coronary artery disease (P <.001), use of class III antiarrhythmic drugs (P <.002), hypertension (P <.002) and metabolic disease (P <.001).
CONCLUSIONS: This prospective survey shows that hospitalizations represent the major cost driver in the treatment of AF patients. Outpatient care programs must be proposed to AF patients in order to avoid readmissions and to reduce the cost of treatment.

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Year:  2004        PMID: 14691429     DOI: 10.1016/s0002-8703(03)00524-6

Source DB:  PubMed          Journal:  Am Heart J        ISSN: 0002-8703            Impact factor:   4.749


  48 in total

Review 1.  Implication from randomized trials of rate and rhythm controls on management of patients with persistent atrial fibrillation.

Authors:  Vincent E Hagens; Dirk J Van Veldhuisen; Harry J G M Crijns; Isabelle C van Gelder
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2.  Improving guideline adherence in the treatment of atrial fibrillation by implementing an integrated chronic care program.

Authors:  J L M Hendriks; R Nieuwlaat; H J M Vrijhoef; R de Wit; H J G M Crijns; R G Tieleman
Journal:  Neth Heart J       Date:  2010-10       Impact factor: 2.380

3.  [Patients suffering from atrial fibrillation in Germany. Characteristics, resource consumption and costs].

Authors:  T Reinhold; S Rosenfeld; F Müller-Riemenschneider; S N Willich; T Meinertz; P Kirchhof; B Brüggenjürgen
Journal:  Herz       Date:  2012-08       Impact factor: 1.443

4.  Pharmacological rhythm and rate control treatment for atrial fibrillation: patient and physician satisfaction.

Authors:  Nils Edvardsson; Anders Westlund; Margareta Thimell; Karin Rise; Alexander Todoran; Tanja Aberg Kurén; John Kindblom; Olle Almgren
Journal:  Patient       Date:  2010-03-01       Impact factor: 3.883

Review 5.  Cost-of-illness studies : a review of current methods.

Authors:  Ebere Akobundu; Jing Ju; Lisa Blatt; C Daniel Mullins
Journal:  Pharmacoeconomics       Date:  2006       Impact factor: 4.981

Review 6.  Dysfunction of the autonomic nervous system in atrial fibrillation.

Authors:  Yutao Xi; Jie Cheng
Journal:  J Thorac Dis       Date:  2015-02       Impact factor: 2.895

Review 7.  Comorbidity of atrial fibrillation and heart failure.

Authors:  Liang-Han Ling; Peter M Kistler; Jonathan M Kalman; Richard J Schilling; Ross J Hunter
Journal:  Nat Rev Cardiol       Date:  2015-12-10       Impact factor: 32.419

8.  Recent advances in pharmacotherapy of atrial fibrillation.

Authors:  J Singh; J S Braich
Journal:  Indian J Pharmacol       Date:  2009-08       Impact factor: 1.200

9.  Knowledge, attitude, and behavior in patients with atrial fibrillation undergoing radiofrequency catheter ablation.

Authors:  Wenhua Xu; Guozhen Sun; Zheng Lin; Minglong Chen; Bing Yang; Hongwu Chen; Kejiang Cao
Journal:  J Interv Card Electrophysiol       Date:  2010-06-16       Impact factor: 1.900

Review 10.  Cost effectiveness of antiarrhythmic medications in patients suffering from atrial fibrillation.

Authors:  Bernd Brüggenjürgen; Stefan Kohler; Nadja Ezzat; Thomas Reinhold; Stefan N Willich
Journal:  Pharmacoeconomics       Date:  2013-03       Impact factor: 4.981

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