Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Molecular determinants of virulence: the structural and functional basis for flavivirus attenuation.

× No keyword cloud information.

10 in total

1. Chimeric dengue 2 PDK-53/West Nile NY99 viruses retain the phenotypic attenuation markers of the candidate PDK-53 vaccine virus and protect mice against lethal challenge with West Nile virus.

Authors: Claire Y-H Huang; Shawn J Silengo; Melissa C Whiteman; Richard M Kinney
Journal: J Virol Date: 2005-06 Impact factor: 5.103

2. A tick-borne Langat virus mutant that is temperature sensitive and host range restricted in neuroblastoma cells and lacks neuroinvasiveness for immunodeficient mice.

Authors: Alexander A Rumyantsev; Brian R Murphy; Alexander G Pletnev
Journal: J Virol Date: 2006-02 Impact factor: 5.103

3. The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome.

Authors: Amber R Engel; Alexander A Rumyantsev; Olga A Maximova; James M Speicher; Brian Heiss; Brian R Murphy; Alexander G Pletnev
Journal: Virology Date: 2010-07-01 Impact factor: 3.616

4. A critical determinant of neurological disease associated with highly pathogenic tick-borne flavivirus in mice.

Authors: Kentaro Yoshii; Yuji Sunden; Kana Yokozawa; Manabu Igarashi; Hiroaki Kariwa; Michael R Holbrook; Ikuo Takashima
Journal: J Virol Date: 2014-02-26 Impact factor: 5.103

5. A single N-linked glycosylation site in the Japanese encephalitis virus prM protein is critical for cell type-specific prM protein biogenesis, virus particle release, and pathogenicity in mice.

Authors: Jeong-Min Kim; Sang-Im Yun; Byung-Hak Song; Youn-Soo Hahn; Chan-Hee Lee; Hyun-Woo Oh; Young-Min Lee
Journal: J Virol Date: 2008-06-04 Impact factor: 5.103

Molecular determinants of virulence: the structural and functional basis for flavivirus attenuation.

1. Chimeric dengue 2 PDK-53/West Nile NY99 viruses retain the phenotypic attenuation markers of the candidate PDK-53 vaccine virus and protect mice against lethal challenge with West Nile virus.

2. A tick-borne Langat virus mutant that is temperature sensitive and host range restricted in neuroblastoma cells and lacks neuroinvasiveness for immunodeficient mice.

3. The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome.

4. A critical determinant of neurological disease associated with highly pathogenic tick-borne flavivirus in mice.

5. A single N-linked glycosylation site in the Japanese encephalitis virus prM protein is critical for cell type-specific prM protein biogenesis, virus particle release, and pathogenicity in mice.

6. Tick-Borne Encephalitis Virus Adaptation in Different Host Environments and Existence of Quasispecies.

Review 7. Flavivirus reverse genetic systems, construction techniques and applications: a historical perspective.

8. Genetic determinants of virulence in pathogenic lineage 2 West Nile virus strains.

9. Dengue 1 diversity and microevolution, French Polynesia 2001-2006: connection with epidemiology and clinics.

10. Comparative full length genome sequence analysis of Usutu virus isolates from Africa.