Literature DB >> 14689088

[Diabetic coma. Management of diabetic ketoacidosis and nonketotic hyperosmolar coma].

J Hensen1.   

Abstract

This review describes the current guidelines of German diabetes association for the management of diabetic coma, both of diabetic ketoacidosis and hyperosmolal coma. The outline focuses on emergency treatment and the management on the intensive care unit, in particular, volume and insulin therapy, and potassium replacement. The delineation of the concept of low insulin therapy is emphasized to avoid the incidence of disequilibrium syndrome. Also, the indications for bicarbonate therapy in diabetic ketoacidosis are critically discussed, as well as phosphate and magnesium replacement. With today's therapeutic possibilities the therapeutic goal, i.e. a low mortality, may be achieved, dependent on the underlying illness.

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Year:  2003        PMID: 14689088     DOI: 10.1007/s00108-003-1058-6

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  28 in total

1.  Therapy of severe diabetic ketoacidosis. Zero-mortality under very-low-dose insulin application.

Authors:  A Wagner; A Risse; H L Brill; V Wienhausen-Wilke; M Rottmann; K Sondern; B Angelkort
Journal:  Diabetes Care       Date:  1999-05       Impact factor: 19.112

2.  Osmoregulation of vasopressin in diabetic ketoacidosis.

Authors:  J A Durr; W H Hoffman; J Hensen; A H Sklar; T el Gammal; C M Steinhart
Journal:  Am J Physiol       Date:  1990-11

3.  Intracerebral crises during treatment of diabetic ketoacidosis.

Authors:  A L Rosenbloom
Journal:  Diabetes Care       Date:  1990-01       Impact factor: 19.112

Review 4.  Low-dose insulin therapy in diabetic ketoacidosis: fact or fiction?

Authors:  A E Kitabchi
Journal:  Diabetes Metab Rev       Date:  1989-06

5.  Cerebral edema and depression of sensorium in nonketotic hyperosmolar coma.

Authors:  A I Arieff; H J Carroll
Journal:  Diabetes       Date:  1974-06       Impact factor: 9.461

Review 6.  The metabolic derangements and treatment of diabetic ketoacidosis.

Authors:  D W Foster; J D McGarry
Journal:  N Engl J Med       Date:  1983-07-21       Impact factor: 91.245

7.  Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics.

Authors:  N Glaser; P Barnett; I McCaslin; D Nelson; J Trainor; J Louie; F Kaufman; K Quayle; M Roback; R Malley; N Kuppermann
Journal:  N Engl J Med       Date:  2001-01-25       Impact factor: 91.245

8.  Diabetic ketoacidosis: low-dose insulin therapy by various routes.

Authors:  J N Fisher; M N Shahshahani; A E Kitabchi
Journal:  N Engl J Med       Date:  1977-08-04       Impact factor: 91.245

9.  Metabolic effects of low-dose insulin therapy on glucose metabolism in diabetic ketoacidosis.

Authors:  L Luzi; E J Barrett; L C Groop; E Ferrannini; R A DeFronzo
Journal:  Diabetes       Date:  1988-11       Impact factor: 9.461

10.  An assessment of insulin action in hyperosmolar hyperglycemic nonketotic diabetic patients.

Authors:  N R Rosenthal; E J Barrett
Journal:  J Clin Endocrinol Metab       Date:  1985-03       Impact factor: 5.958

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