Literature DB >> 14688438

Intravitreal r-TPA and gas injection in traumatic submacular hemorrhage.

Detlef Holland1, Burkhard Wiechens.   

Abstract

AIM: To present the technique and efficiency of intravitreal recombinant tissue plasminogen activator (r-TPA) and gas injection in acute submacular hemorrhage (SMH) due to traumatic choroidal rupture. PATIENTS AND METHODS: 0.4 ml of sulfur hexafluoride was injected into the vitreous cavity in 2 patients with SMH due to traumatic choroidal rupture. In 1 patient gas injection was combined with 50 microg r-TPA. Both patients were closely followed.
RESULTS: Preoperative visual acuity was 20/125 in one eye and 20/100 in the other. At the end of the follow-up, visual acuity had improved to 20/32 in both eyes.
CONCLUSION: r-TPA and gas injection into the vitreous body may be an efficient therapy in patients with submacular hemorrhage due to choroidal rupture. Copyright 2004 S. Karger AG, Basel

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Year:  2004        PMID: 14688438     DOI: 10.1159/000074569

Source DB:  PubMed          Journal:  Ophthalmologica        ISSN: 0030-3755            Impact factor:   3.250


  7 in total

1.  Reduction of steroid-induced intraocular pressure elevation in sheep by tissue plasminogen activator.

Authors:  Rosana Gerometta; Sandeep Kumar; Shaily Shah; Larry Alvarez; Oscar Candia; John Danias
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-12-03       Impact factor: 4.799

2.  Choroidal rupture and optic nerve injury with equipment designated as 'child-safe'.

Authors:  Robert Petrarca; Manuel Saldana
Journal:  BMJ Case Rep       Date:  2012-08-27

3.  Intravitreal tPA Injection and Pneumatic Displacement for Submacular Hemorrhage in a 10-Year-Old Child.

Authors:  Takayuki Tsuyama; Hiroshi Hirose; Tomohiro Hattori
Journal:  Case Rep Ophthalmol Med       Date:  2016-09-18

4.  Traumatic Submacular Hemorrhage with Macular Hole Repaired by Pneumatic Displacement and Intravitreal t-PA Injection.

Authors:  Amy A Mehta; Jay Berdia; Lilly H Wagner; Irene Choi; Brandon B Johnson
Journal:  Case Rep Ophthalmol Med       Date:  2017-06-11

5.  Airbag-Associated Severe Blunt Eye Injury Causes Choroidal Rupture and Retinal Hemorrhage: A Case Report.

Authors:  Shih Hao Wang; Chen Chee Lim; Yu Ti Teng
Journal:  Case Rep Ophthalmol       Date:  2017-01-16

6.  Successful displacement of a traumatic submacular hemorrhage in a 13-year-old boy treated by vitrectomy, subretinal injection of tissue plasminogen activator and intravitreal air tamponade: a case report.

Authors:  Shinichiro Doi; Shuhei Kimura; Yuki Morizane; Yusuke Shiode; Mio Hosokawa; Masayuki Hirano; Mika Hosogi; Atsushi Fujiwara; Kazuhisa Miyamoto; Fumio Shiraga
Journal:  BMC Ophthalmol       Date:  2015-08-07       Impact factor: 2.209

Review 7.  Traumatic submacular hemorrhage: available treatment options and synthesis of the literature.

Authors:  Giamberto Casini; Pasquale Loiudice; Martina Menchini; Francesco Sartini; Stefano De Cillà; Michele Figus; Marco Nardi
Journal:  Int J Retina Vitreous       Date:  2019-12-11
  7 in total

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