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Literature DB >> 1468635

Overdominant vs. frequency-dependent selection at MHC loci.

R W Slade, H I McCallum.

Abstract

Entities: Gene

Mesh：

Year: 1992 PMID： 1468635 PMCID： PMC1205221

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

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63 in total

1. Heterozygote advantage fails to explain the high degree of polymorphism of the MHC.

Authors: Rob J De Boer; José A M Borghans; Michiel van Boven; Can Keşmir; Franz J Weissing
Journal: Immunogenetics Date: 2004-01-13 Impact factor: 2.846

2. MHC polymorphism under host-pathogen coevolution.

Authors: José A M Borghans; Joost B Beltman; Rob J De Boer
Journal: Immunogenetics Date: 2004-01-13 Impact factor: 2.846

3. Natural selection and the distribution of identity-by-descent in the human genome.

Authors: Anders Albrechtsen; Ida Moltke; Rasmus Nielsen
Journal: Genetics Date: 2010-06-30 Impact factor: 4.562

4. Heterogeneity of dN/dS Ratios at the Classical HLA Class I Genes over Divergence Time and Across the Allelic Phylogeny.

Authors: Bárbara Domingues Bitarello; Rodrigo dos Santos Francisco; Diogo Meyer
Journal: J Mol Evol Date: 2015-11-14 Impact factor: 2.395

5. High levels of sequence polymorphism and linkage disequilibrium at the telomere of 12q: implications for telomere biology and human evolution.

Authors: D M Baird; J Coleman; Z H Rosser; N J Royle
Journal: Am J Hum Genet Date: 2000-01 Impact factor: 11.025

10. A sequence-based approach demonstrates that balancing selection in classical human leukocyte antigen (HLA) loci is asymmetric.

Authors: Paola G Bronson; Steven J Mack; Henry A Erlich; Montgomery Slatkin
Journal: Hum Mol Genet Date: 2012-10-12 Impact factor: 6.150

Overdominant vs. frequency-dependent selection at MHC loci.

1. Heterozygote advantage fails to explain the high degree of polymorphism of the MHC.

2. MHC polymorphism under host-pathogen coevolution.

3. Natural selection and the distribution of identity-by-descent in the human genome.

4. Heterogeneity of dN/dS Ratios at the Classical HLA Class I Genes over Divergence Time and Across the Allelic Phylogeny.

5. High levels of sequence polymorphism and linkage disequilibrium at the telomere of 12q: implications for telomere biology and human evolution.

6. Multiplicative fitness, rapid haplotype discovery, and fitness decay explain evolution of human MHC.

7. Distinct evolutionary strategies of human leucocyte antigen loci in pathogen-rich environments.

8. Patterns of selection and polymorphism of innate immunity genes in bumblebees (Hymenoptera: Apidae).

Review 9. How pathogens drive genetic diversity: MHC, mechanisms and misunderstandings.

10. A sequence-based approach demonstrates that balancing selection in classical human leukocyte antigen (HLA) loci is asymmetric.