Sanziana Roman1. 1. Yale University School of Medicine, New Haven, CT 06520, USA. Sanziana.roman@yale.edu
Abstract
PURPOSE: Pheochromocytomas and paragangliomas are rare tumors of chromaffin cell origin. Their identification is likely increasing owing to the increased use of radiographic images detecting incidental adrenal masses. RECENT FINDINGS: The pathophysiology of hypertension induced by the release of catecholamines and newly discovered peptides has been shown to be more complex than the concept of episodic catecholamine release. SUMMARY: This review looks at the most recent advances in the physiology and molecular basis of these tumors.
PURPOSE:Pheochromocytomas and paragangliomas are rare tumors of chromaffin cell origin. Their identification is likely increasing owing to the increased use of radiographic images detecting incidental adrenal masses. RECENT FINDINGS: The pathophysiology of hypertension induced by the release of catecholamines and newly discovered peptides has been shown to be more complex than the concept of episodiccatecholamine release. SUMMARY: This review looks at the most recent advances in the physiology and molecular basis of these tumors.