Literature DB >> 14684319

Phenolic thiazoles as novel orally-active neuroprotective agents.

Jeremiah J Harnett1, Veronique Roubert, Christine Dolo, Christelle Charnet, Brigitte Spinnewyn, Sylvie Cornet, Alain Rolland, Jean-Gregoire Marin, Dennis Bigg, Pierre-E Chabrier.   

Abstract

Novel phenolic thiazoles compounds were prepared which demonstrated potent antioxidant activity and potent in vivo neuroprotection in mitochondrial toxin models and also possess good oral bioavailability.

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Year:  2004        PMID： 14684319     DOI： 10.1016/j.bmcl.2003.09.077

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  5 in total

1.  Synthesis and antimicrobial evaluation of some novel thiazole, pyridone, pyrazole, chromene, hydrazone derivatives bearing a biologically active sulfonamide moiety.

Authors:  Elham S Darwish; Azza M Abdel Fattah; Fawzy A Attaby; Oqba N Al-Shayea
Journal:  Int J Mol Sci       Date:  2014-01-17       Impact factor: 5.923

2.  Synthesis, Characterization and Bioassay of Novel Substituted 1-(3-(1,3-Thiazol-2-yl)phenyl)-5-oxopyrrolidines.

Authors:  Birutė Sapijanskaitė-Banevič; Božena Šovkovaja; Rita Vaickelionienė; Jūratė Šiugždaitė; Eglė Mickevičiūtė
Journal:  Molecules       Date:  2020-05-22       Impact factor: 4.411

3.  Synthesis and biological activity of 3-[phenyl(1,3-thiazol-2-yl)-amino]propanoic acids and their derivatives.

Authors:  Vytautas Mickevičius; Aušra Voskienė; Ilona Jonuškienė; Ramūnė Kolosej; Jūratė Šiugždaitė; Petras Rimantas Venskutonis; Rita Kazernavičiūtė; Zita Brazienė; Elena Jakienė
Journal:  Molecules       Date:  2013-12-05       Impact factor: 4.411

4.  Synthesis, antimicrobial and cytotoxic activities of some novel thiazole clubbed 1,3,4-oxadiazoles.

Authors:  N C Desai; Nayan Bhatt; Hardik Somani; Amit Trivedi
Journal:  Eur J Med Chem       Date:  2013-06-19       Impact factor: 6.514

5.  In Vitro Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual DNA Gyrase and DHFR Inhibitors against MDR Pathogens.

Authors:  Hazem Ali Mohamed; Yousry A Ammar; Gameel A M Elhagali; Hassan A Eyada; Dina S Aboul-Magd; Ahmed Ragab
Journal:  ACS Omega       Date:  2022-02-03
  5 in total

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