Literature DB >> 14683424

Digene Corporation.

Richard Obiso1, Attila Lorincz.   

Abstract

Digene Corporation is a molecular diagnostics company that develops, manufactures and markets proprietary gene-based testing systems for the screening, monitoring and diagnosis of human diseases. The company's primary focus is in women's cancers and infectious diseases. Our proprietary, patented Hybrid Capture((R)) technology has been successfully applied to the development of diagnostic tests for human papillomavirus (HPV), Chlamydia, Gonorrhea, hepatitis B virus and cytomegalovirus. Digene's Hybrid Capture 2 (hc2) trade mark HPV DNA test has now been established as part of the standard of care for cervical cancer screening in the US. We are focusing our research and development activities on support and improvement of existing product lines as well as the development of several new products. We have several ongoing basic research programs with the goal of developing improved molecular diagnostic assay systems for the detection of HPV and other targets of interest in the area of women's cancers and infectious diseases. Digene's goal is to establish primary screening by the Hybrid Capture HPV DNA Test as the worldwide standard of care for cervical cancer screening.

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Year:  2004        PMID: 14683424     DOI: 10.1517/phgs.5.1.129.25678

Source DB:  PubMed          Journal:  Pharmacogenomics        ISSN: 1462-2416            Impact factor:   2.533


  7 in total

1.  Correlation of cellular immunity with human papillomavirus 16 status and outcome in patients with advanced oropharyngeal cancer.

Authors:  Derrick Wansom; Emily Light; Frank Worden; Mark Prince; Susan Urba; Douglas B Chepeha; Kitrina Cordell; Avraham Eisbruch; Jeremy Taylor; Nisha D'Silva; Jeffrey Moyer; Carol R Bradford; David Kurnit; Bhavna Kumar; Thomas E Carey; Gregory T Wolf
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2010-12

2.  Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population.

Authors:  Lisbeth Herrera-Romano; Nora Fernández-Tamayo; Eduardo Gómez-Conde; Juan M Reyes-Cardoso; Felipe Ortiz-Gutierrez; Guillermo Ceballos; Alejandra Valdivia; Patricia Piña; Mauricio Salcedo
Journal:  Med Oncol       Date:  2011-09-11       Impact factor: 3.064

3.  EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer.

Authors:  Bhavna Kumar; Kitrina G Cordell; Julia S Lee; Francis P Worden; Mark E Prince; Huong H Tran; Gregory T Wolf; Susan G Urba; Douglas B Chepeha; Theodoros N Teknos; Avraham Eisbruch; Christina I Tsien; Jeremy M G Taylor; Nisha J D'Silva; Kun Yang; David M Kurnit; Joshua A Bauer; Carol R Bradford; Thomas E Carey
Journal:  J Clin Oncol       Date:  2008-05-12       Impact factor: 44.544

4.  Chemoselection as a strategy for organ preservation in advanced oropharynx cancer: response and survival positively associated with HPV16 copy number.

Authors:  Francis P Worden; Bhavna Kumar; Julia S Lee; Gregory T Wolf; Kitrina G Cordell; Jeremy M G Taylor; Susan G Urba; Avraham Eisbruch; Theodoros N Teknos; Douglas B Chepeha; Mark E Prince; Christina I Tsien; Nisha J D'Silva; Kun Yang; David M Kurnit; Heidi L Mason; Tamara H Miller; Nancy E Wallace; Carol R Bradford; Thomas E Carey
Journal:  J Clin Oncol       Date:  2008-05-12       Impact factor: 44.544

5.  Evaluation of a newly developed GenoArray human papillomavirus (HPV) genotyping assay and comparison with the Roche Linear Array HPV genotyping assay.

Authors:  Stephanie S Liu; Rebecca C Y Leung; Karen K L Chan; Annie N Y Cheung; Hextan Y S Ngan
Journal:  J Clin Microbiol       Date:  2009-12-30       Impact factor: 5.948

6.  Prevalence and predictors of high-risk human papillomavirus infection in a population-based sample of women in rural Uganda.

Authors:  Stephen Asiimwe; Christopher C Whalen; Daniel J Tisch; Elioda Tumwesigye; Ajay K Sethi
Journal:  Int J STD AIDS       Date:  2008-09       Impact factor: 1.359

7.  Development and evaluation of a PCR and mass spectroscopy (PCR-MS)-based method for quantitative, type-specific detection of human papillomavirus.

Authors:  Divya A Patel; Yang-Jen Shih; Duane W Newton; Claire W Michael; Paul A Oeth; Michael D Kane; Anthony W Opipari; Mack T Ruffin; Linda M Kalikin; David M Kurnit
Journal:  J Virol Methods       Date:  2009-05-03       Impact factor: 2.014

  7 in total

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