| Literature DB >> 14682758 |
David R Williams1, Samarjit Patnaik, Scott V Plummer.
Abstract
A convergent, second generation formal synthesis of (+)-Leucascandrolide A (1) has been efficiently achieved by providing a flexible, enantiocontrolled strategy toward the bioactive macrolactone component. Advancements for stereocontrol in asymmetric allylation methodology are discussed. Efforts feature novel results for reductions using the Terashima hydride reagent. [structure: see text]Entities:
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Year: 2003 PMID： 14682758 DOI： 10.1021/ol036071v
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005