Literature DB >> 14681375

THGS: a web-based database of Transmembrane Helices in Genome Sequences.

S A Fernando1, P Selvarani, Soma Das, Ch Kiran Kumar, Sukanta Mondal, S Ramakumar, K Sekar.   

Abstract

Transmembrane Helices in Genome Sequences (THGS) is an interactive web-based database, developed to search the transmembrane helices in the user-interested gene sequences available in the Genome Database (GDB). The proposed database has provision to search sequence motifs in transmembrane and globular proteins. In addition, the motif can be searched in the other sequence databases (Swiss-Prot and PIR) or in the macromolecular structure database, Protein Data Bank (PDB). Further, the 3D structure of the corresponding queried motif, if it is available in the solved protein structures deposited in the Protein Data Bank, can also be visualized using the widely used graphics package RASMOL. All the sequence databases used in the present work are updated frequently and hence the results produced are up to date. The database THGS is freely available via the world wide web and can be accessed at http:// pranag.physics.iisc.ernet.in/thgs/ or http://144.16. 71.10/thgs/.

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Year:  2004        PMID: 14681375      PMCID: PMC308864          DOI: 10.1093/nar/gkh130

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  14 in total

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2.  Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.

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Journal:  J Mol Biol       Date:  2000-02-25       Impact factor: 5.469

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