BACKGROUND/ OBJECTIVES: The goal of this study was to determine the influence of chronic obstructive pulmonary disease (COPD) on health-related quality of life (HRQL) independent of comorbidity. METHODS: Patients with COPD in general practice, >/=40 years, were selected. To recruit controls, a random sample of persons without COPD and >/=40 years, was taken. HRQL was assessed with the SF-36 and comorbidity was determined by questionnaire. RESULTS: The influence of COPD on HRQL independent of comorbidity (represented by adjusted regression coefficients) was significant for physical functioning (-27.6), role functioning due to physical problems (-21.6), vitality (-14.4), and general health (-25.7), and was minor and not significant for social functioning (-5.6), mental health (-1.3), role functioning due to emotional problems (-2.7), and bodily pain (-2.5). Comorbidity contributed significantly to the HRQL of all domains (-7.6 to -27.1). CONCLUSIONS: COPD patients can be impaired in all domains of HRQL. However, impairments in physical functioning, vitality, and general health are related to COPD and to some extent to comorbidity, while impairments in social and emotional functioning do not seem to be related to COPD, but only to comorbidity.
BACKGROUND/ OBJECTIVES: The goal of this study was to determine the influence of chronic obstructive pulmonary disease (COPD) on health-related quality of life (HRQL) independent of comorbidity. METHODS:Patients with COPD in general practice, >/=40 years, were selected. To recruit controls, a random sample of persons without COPD and >/=40 years, was taken. HRQL was assessed with the SF-36 and comorbidity was determined by questionnaire. RESULTS: The influence of COPD on HRQL independent of comorbidity (represented by adjusted regression coefficients) was significant for physical functioning (-27.6), role functioning due to physical problems (-21.6), vitality (-14.4), and general health (-25.7), and was minor and not significant for social functioning (-5.6), mental health (-1.3), role functioning due to emotional problems (-2.7), and bodily pain (-2.5). Comorbidity contributed significantly to the HRQL of all domains (-7.6 to -27.1). CONCLUSIONS:COPDpatients can be impaired in all domains of HRQL. However, impairments in physical functioning, vitality, and general health are related to COPD and to some extent to comorbidity, while impairments in social and emotional functioning do not seem to be related to COPD, but only to comorbidity.
Authors: Jay H Ryu; Joel Moss; Gerald J Beck; Jar-Chi Lee; Kevin K Brown; Jeffrey T Chapman; Geraldine A Finlay; Eric J Olson; Stephen J Ruoss; Janet R Maurer; Thomas A Raffin; Hannah H Peavy; Kevin McCarthy; Angelo Taveira-Dasilva; Francis X McCormack; Nilo A Avila; Rosamma M Decastro; Susan S Jacobs; Mario Stylianou; Barry L Fanburg Journal: Am J Respir Crit Care Med Date: 2005-10-06 Impact factor: 21.405
Authors: Ji Young Hong; Sang A Lee; Song Yee Kim; Kyung Soo Chung; Sung Woo Moon; Eun Young Kim; Ji Ye Jung; Moo Suk Park; Young Sam Kim; Se Kyu Kim; Joon Chang; Young Ae Kang Journal: Qual Life Res Date: 2014-06-08 Impact factor: 4.147
Authors: Roeland Mm Geijer; Alfred Pe Sachs; Theo Jm Verheij; Huib Am Kerstjens; Marijke M Kuyvenhoven; Arno W Hoes Journal: Br J Gen Pract Date: 2007-06 Impact factor: 5.386
Authors: Julia A E Walters; Helen Cameron-Tucker; Helen Courtney-Pratt; Mark Nelson; Andrew Robinson; Jenn Scott; Paul Turner; E Haydn Walters; Richard Wood-Baker Journal: BMC Fam Pract Date: 2012-06-13 Impact factor: 2.497