Literature DB >> 14680626

Chemokines in eosinophil-associated gastrointestinal disorders.

Simon P Hogan1, Marc E Rothenberg, Elizabeth Forbes, Vanessa E Smart, Klaus I Matthaei, Paul S Foster.   

Abstract

Eosinophil-associated gastrointestinal disorders (EGDs) are characterized by a pronounced cellular inflammation. Recent clinical and experimental investigations have implicated a family of molecules known as chemokines in the regulation of leukocyte recruitment in these diseases. The underlying cellular and molecular mechanisms involved in chemokine-mediated cellular infiltration are largely unknown. In this review, we describe the role of CD4+ T cells and eosinophils in the clinical manifestations of EGDs and discuss the current understanding of the role of chemokines in the recruitment of these cells in the expression of diseases.

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Year:  2004        PMID： 14680626     DOI： 10.1007/s11882-004-0047-8

Source DB:  PubMed          Journal:  Curr Allergy Asthma Rep        ISSN： 1529-7322            Impact factor:   4.919


  47 in total

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Journal:  J Immunol       Date:  2002-03-01       Impact factor: 5.422

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9.  Eotaxin-2 activates chemotaxis-related events and release of reactive oxygen species via pertussis toxin-sensitive G proteins in human eosinophils.

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10.  CCL25 mediates the localization of recently activated CD8alphabeta(+) lymphocytes to the small-intestinal mucosa.

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  5 in total

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Journal:  Immunol Allergy Clin North Am       Date:  2009-02       Impact factor: 3.479

3.  Enhanced levels of chemokines and their receptors in the colon of microscopic colitis patients indicate mixed immune cell recruitment.

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4.  Reduced IL-37 Production Increases Spontaneous Chemokine Expressions in Colon Epithelial Cells.

Authors:  Sezin Günaltay; Mohammed Ghiboub; Olof Hultgren; Elisabeth Hultgren Hörnquist
Journal:  Dig Dis Sci       Date:  2017-01-02       Impact factor: 3.199

Review 5.  Eosinophil Function in Eosinophil-associated Gastrointestinal Disorders.

Authors:  Simon P Hogan; Marc E Rothenberg
Journal:  Curr Allergy Asthma Rep       Date:  2006-02       Impact factor: 4.919
  5 in total

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