Literature DB >> 14680216

Cell-permeable small molecule probes for site-specific labeling of proteins.

Dawn S Y Yeo1, Rajavel Srinivasan, Mahesh Uttamchandani, Grace Y J Chen, Qing Zhu, Shao Q Yao.   

Abstract

We have successfully synthesized a number of small molecule probes designed for site-specific labeling of N-terminal cysteine-containing proteins expressed in live cells. Their utility for site-specific, covalent modifications of proteins was successfully demonstrated with purified proteins in vitro, and with live bacterial cells in vivo.

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Year:  2003        PMID： 14680216     DOI： 10.1039/b309196a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

Review 1.  Application of microarrays in high-throughput enzymatic profiling.

Authors:  Mahesh Uttamchandani; Xuan Huang; Grace Y J Chen; Lay-Pheng Tan; Shao Q Yao
Journal:  Mol Biotechnol       Date:  2004-11       Impact factor: 2.695

2.  Site-specific fluorescent labeling of poly-histidine sequences using a metal-chelating cysteine.

Authors:  Beena Krishnan; Aneta Szymanska; Lila M Gierasch
Journal:  Chem Biol Drug Des       Date:  2007-01       Impact factor: 2.817

3.  Epicocconone, a new cell-permeable long Stokes' shift fluorescent stain for live cell imaging and multiplexing.

Authors:  H-Y Choi; D A Veal; P Karuso
Journal:  J Fluoresc       Date:  2005-12-03       Impact factor: 2.217

4.  Chemical tags for labeling proteins inside living cells.

Authors:  Chaoran Jing; Virginia W Cornish
Journal:  Acc Chem Res       Date:  2011-08-31       Impact factor: 22.384

5.  A biocompatible condensation reaction for the labeling of terminal cysteine residues on proteins.

Authors:  Hongjun Ren; Fei Xiao; Ke Zhan; Young-Pil Kim; Hexin Xie; Zuyong Xia; Jianghong Rao
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

Review 6.  Site-specific functionalization of proteins and their applications to therapeutic antibodies.

Authors:  Remko van Vught; Roland J Pieters; Eefjan Breukink
Journal:  Comput Struct Biotechnol J       Date:  2014-02-14       Impact factor: 7.271

7.  High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA.

Authors:  Patrick T O'Kane; Quentin M Dudley; Aislinn K McMillan; Michael C Jewett; Milan Mrksich
Journal:  Sci Adv       Date:  2019-06-05       Impact factor: 14.136

8.  Bioorthogonal chemistry: fishing for selectivity in a sea of functionality.

Authors:  Ellen M Sletten; Carolyn R Bertozzi
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

Review 9.  Semi-synthesis of labeled proteins for spectroscopic applications.

Authors:  Lucia De Rosa; Anna Russomanno; Alessandra Romanelli; Luca Domenico D'Andrea
Journal:  Molecules       Date:  2013-01-02       Impact factor: 4.411
  9 in total

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