| Literature DB >> 14679066 |
Yoichi Oikawa1, Akira Shimada, Satoru Yamada, Yoshiko Motohashi, Yoshinori Nakagawa, Jun-Ichiro Irie, Taro Maruyama, Takao Saruta.
Abstract
A numerical and functional deficit of natural killer T (NKT) cells has been reported to be associated with the pathogenesis of Caucasian patients with type 1 diabetes. However, a conflicting finding of a higher frequency of NKT cells (Valpha24+ Vbeta11+ T cells) was observed in islet-associated Ab+ and Ab- Japanese "classic" type 1 diabetes. Here, we combined the data of NKT cell frequency in Ab+ and Ab- "classic" type 1 diabetic patients and then analyzed the relationship between NKT cell frequency and disease activity.Entities:
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Year: 2003 PMID： 14679066 DOI： 10.1196/annals.1288.033
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691