Literature DB >> 14678835

Rig-1 a new member of Robo family genes exhibits distinct pattern of expression during mouse development.

Laura Camurri1, Elvira Mambetisaeva, Vasi Sundaresan.   

Abstract

The Robo genes encode a family of proteins that are the receptors for the midline repellent Slits and play a role in axon guidance. In addition to Robo1 and Robo2, Rig-1 has been recently identified in mouse as a novel member of the Robo family of proteins. As a first step in elucidating the role of Rig-1 during vertebrate development, we characterised the expression of Rig-1 by in situ hybridisation together with Robo1 and Robo2 in the spinal cord and other tissues of the mouse embryo. Our results show that Rig-1 has a dynamic pattern of expression in the developing CNS. In the spinal cord Rig-1 shows overlapping but distinct pattern of expression with Robo1 and Robo2.

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Year:  2004        PMID: 14678835     DOI: 10.1016/s1567-133x(03)00142-x

Source DB:  PubMed          Journal:  Gene Expr Patterns        ISSN: 1567-133X            Impact factor:   1.224


  12 in total

Review 1.  Transcriptional regulation of guidance at the midline and in motor circuits.

Authors:  Aref Arzan Zarin; Jamshid Asadzadeh; Juan-Pablo Labrador
Journal:  Cell Mol Life Sci       Date:  2013-08-06       Impact factor: 9.261

2.  Robo1 modulates proliferation and neurogenesis in the developing neocortex.

Authors:  Mason L Yeh; Yuko Gonda; Mathilda T M Mommersteeg; Melissa Barber; Athena R Ypsilanti; Carina Hanashima; John G Parnavelas; William D Andrews
Journal:  J Neurosci       Date:  2014-04-16       Impact factor: 6.167

Review 3.  Human disorders of axon guidance.

Authors:  Alicia A Nugent; Adrianne L Kolpak; Elizabeth C Engle
Journal:  Curr Opin Neurobiol       Date:  2012-03-05       Impact factor: 6.627

4.  Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain.

Authors:  Itzel Ricaño-Cornejo; Amy L Altick; Claudia M García-Peña; Hikmet Feyza Nural; Diego Echevarría; Amaya Miquelajáuregui; Grant S Mastick; Alfredo Varela-Echavarría
Journal:  J Neurosci Res       Date:  2011-06-17       Impact factor: 4.164

5.  Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain.

Authors:  Luis R Hernández-Miranda; Anna Cariboni; Clare Faux; Christiana Ruhrberg; Jin Hyung Cho; Jean-François Cloutier; Britta J Eickholt; John G Parnavelas; William D Andrews
Journal:  J Neurosci       Date:  2011-04-20       Impact factor: 6.167

6.  Expression of Slit and Robo genes in the developing mouse heart.

Authors:  Caroline Medioni; Nicolas Bertrand; Karim Mesbah; Bruno Hudry; Laurent Dupays; Orit Wolstein; Andrew J Washkowitz; Virginia E Papaioannou; Timothy J Mohun; Richard P Harvey; Stéphane Zaffran
Journal:  Dev Dyn       Date:  2010-12       Impact factor: 3.780

7.  The Slit receptor Robo1 is predominantly expressed via the Dutt1 alternative promoter in pioneer neurons in the embryonic mouse brain and spinal cord.

Authors:  Hikmet Feyza Nural; W Todd Farmer; Grant S Mastick
Journal:  Gene Expr Patterns       Date:  2007-08-07       Impact factor: 1.224

8.  Epigenetic silencing of spermatocyte-specific and neuronal genes by SUMO modification of the transcription factor Sp3.

Authors:  Bastian Stielow; Imme Krüger; Rolf Diezko; Florian Finkernagel; Nynke Gillemans; John Kong-a-San; Sjaak Philipsen; Guntram Suske
Journal:  PLoS Genet       Date:  2010-11-11       Impact factor: 5.917

9.  Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesis.

Authors:  Joanna C Jen; Wai-Man Chan; Thomas M Bosley; Jijun Wan; Janai R Carr; Udo Rüb; David Shattuck; Georges Salamon; Lili C Kudo; Jing Ou; Doris D M Lin; Mustafa A M Salih; Tülay Kansu; Hesham Al Dhalaan; Zayed Al Zayed; David B MacDonald; Bent Stigsby; Andreas Plaitakis; Emmanuel K Dretakis; Irene Gottlob; Christina Pieh; Elias I Traboulsi; Qing Wang; Lejin Wang; Caroline Andrews; Koki Yamada; Joseph L Demer; Shaheen Karim; Jeffry R Alger; Daniel H Geschwind; Thomas Deller; Nancy L Sicotte; Stanley F Nelson; Robert W Baloh; Elizabeth C Engle
Journal:  Science       Date:  2004-04-22       Impact factor: 47.728

10.  The role of Robo3 in the development of cortical interneurons.

Authors:  Melissa Barber; Thomas Di Meglio; William D Andrews; Luis R Hernández-Miranda; Fujio Murakami; Alain Chédotal; John G Parnavelas
Journal:  Cereb Cortex       Date:  2009-04-14       Impact factor: 5.357

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