| Literature DB >> 14678835 |
Laura Camurri1, Elvira Mambetisaeva, Vasi Sundaresan.
Abstract
The Robo genes encode a family of proteins that are the receptors for the midline repellent Slits and play a role in axon guidance. In addition to Robo1 and Robo2, Rig-1 has been recently identified in mouse as a novel member of the Robo family of proteins. As a first step in elucidating the role of Rig-1 during vertebrate development, we characterised the expression of Rig-1 by in situ hybridisation together with Robo1 and Robo2 in the spinal cord and other tissues of the mouse embryo. Our results show that Rig-1 has a dynamic pattern of expression in the developing CNS. In the spinal cord Rig-1 shows overlapping but distinct pattern of expression with Robo1 and Robo2.Entities:
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Year: 2004 PMID: 14678835 DOI: 10.1016/s1567-133x(03)00142-x
Source DB: PubMed Journal: Gene Expr Patterns ISSN: 1567-133X Impact factor: 1.224