Anders Molander1, Gunnar Dahlén. 1. Department of Endodontology/Oral Diagnosis, Göteborg University, Sweden. a.molander@odontologi.gu.se
Abstract
OBJECTIVE: We evaluated the intracanal antibacterial potential of tetracycline or erythromycin mixed with calcium hydroxide (CH) against enterococci in vivo. STUDY DESIGN: Fifty-five teeth in which enterococci were present were dressed for 1 month with either tetracycline (28 teeth) or erythromycin (27 teeth) mixed with CH. RESULTS: The tetracycline mixture was effective against enterococci in 22 teeth (79%). In 7 teeth, other microorganisms were recovered, resulting in a total antimicrobial effect of 54%. The corresponding results for erythromycin were 96% and 56%. CONCLUSIONS: The antimicrobial treatment of CH in combination with either erythromycin or tetracycline had a significant effect on enterococci, but the overall antimicrobial effect was relatively weak. Erythromycin mixed with CH seems to be a valuable option in the battle against monoinfections of enterococci.
OBJECTIVE: We evaluated the intracanal antibacterial potential of tetracycline or erythromycin mixed with calcium hydroxide (CH) against enterococci in vivo. STUDY DESIGN: Fifty-five teeth in which enterococci were present were dressed for 1 month with either tetracycline (28 teeth) or erythromycin (27 teeth) mixed with CH. RESULTS: The tetracycline mixture was effective against enterococci in 22 teeth (79%). In 7 teeth, other microorganisms were recovered, resulting in a total antimicrobial effect of 54%. The corresponding results for erythromycin were 96% and 56%. CONCLUSIONS: The antimicrobial treatment of CH in combination with either erythromycin or tetracycline had a significant effect on enterococci, but the overall antimicrobial effect was relatively weak. Erythromycin mixed with CH seems to be a valuable option in the battle against monoinfections of enterococci.
Authors: E De Leener; A Martel; E M De Graef; J Top; P Butaye; F Haesebrouck; R Willems; A Decostere Journal: Appl Environ Microbiol Date: 2005-05 Impact factor: 4.792