Literature DB >> 14676494

Activated charcoal laryngitis in an intubated patient.

Alejandro Donoso1, Marcela Linares, José León, Gloria Rojas, Cristián Valverde, Milena Ramírez, Bernd Oberpaur.   

Abstract

UNLABELLED: Activated charcoal is useful in the management of poisonings, but it is not harmless. We report the case of a patient who developed obstructive laryngitis secondary to aspiration of activated charcoal with a protected airway. CASE: A 2-year-old girl presented acute mental alteration secondary to presumed poisoning. Mechanical ventilation was initiated, and a single dose of activated charcoal was administered. She had an episode of vomiting during the respiratory weaning. Black-tinted tracheal secretions were suctioned through the tube immediately. Pulmonary auscultation and radiologic examination were normal. When she was extubed, she developed obstructive laryngitis. Fiberbronchoscopy was performed and showed edema and a significant amount of charcoal particles on the epiglottis, arytenoids, and arytenoepiglottic folds. Charcoal particles were removed by bronchoscopy successfully. Later evolution was normal, and no symptoms were present when she was discharged at home. COMMENTS: Obstructive laryngitis is a new major complication of activated charcoals use in upper airway. It is remarkable that this complication occurred in a protected airway. Charcoal is not an innocuous agent. This case shows that nasogastric administration of activated charcoals presents a significant degree of risk.

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Year:  2003        PMID: 14676494     DOI: 10.1097/01.pec.0000101586.65509.d9

Source DB:  PubMed          Journal:  Pediatr Emerg Care        ISSN: 0749-5161            Impact factor:   1.454


  3 in total

1.  The role of iNOS inhibitors on lung injury induced by gastrointestinal decontamination agents aspiration.

Authors:  Ahmet Güzel; Aygül Güzel; Mithat Günaydin; Hasan Alaçam; Osman Saliş; M Sükrü Paksu; Naci Murat; Ayhan Gacar; Tolga Güvenç
Journal:  J Mol Histol       Date:  2012-02-29       Impact factor: 2.611

Review 2.  Activated charcoal for acute overdose: a reappraisal.

Authors:  David N Juurlink
Journal:  Br J Clin Pharmacol       Date:  2015-11-09       Impact factor: 4.335

Review 3.  Endotracheal Intubation in the Pharmaceutical-Poisoned Patient: a Narrative Review of the Literature.

Authors:  Glenn A Burket; B Zane Horowitz; Robert G Hendrickson; Gillian A Beauchamp
Journal:  J Med Toxicol       Date:  2020-05-11
  3 in total

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