Literature DB >> 14675318

A new technique to map vulva microcirculation using laser Doppler perfusion imager.

J Saravanamuthu1, A M Seifalian, W M Reid, A B Maclean.   

Abstract

The location of the vulva has had limited technologic progress in the assessment of the skin microcirculation and its application to clinical practice. Our group previously demonstrated increased perfusion in vulvar cancer compared to adjacent uninvolved skin with the laser Doppler flowmetry (LDF). The LDF is severely limited by its low spatial resolution ( approximately 1 mm(2)) and pressure involved in positioning of the probe, which may affect value of the underlying tissue perfusion. Topographic perfusion mapping of the whole vulvar skin using LDF is also time consuming and is not clinically practical. We describe for the first time the application of the novel laser Doppler perfusion imager (LDPI) to map vulvar skin blood flow and give example in two cases with well-defined vulvar pathology-psoriasis and lichen sclerosus with invasive neoplasia-and discuss the potential of LDPI to study vulvar skin blood flow.

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Year:  2003        PMID: 14675318     DOI: 10.1111/j.1525-1438.2003.13047.x

Source DB:  PubMed          Journal:  Int J Gynecol Cancer        ISSN: 1048-891X            Impact factor:   3.437


  2 in total

1.  An evaluation of the effect of a gastric ischemia-reperfusion model with laser Doppler blood perfusion imaging.

Authors:  Dong Zhang; Shunyue Li; Shuyou Wang; Huimin Ma
Journal:  Lasers Med Sci       Date:  2006-10-11       Impact factor: 3.161

2.  Concurrent Reflectance Confocal Microscopy and Laser Doppler Flowmetry to Improve Skin Cancer Imaging: A Monte Carlo Model and Experimental Validation.

Authors:  Alireza Mowla; Thomas Taimre; Yah Leng Lim; Karl Bertling; Stephen J Wilson; Tarl W Prow; H Peter Soyer; Aleksandar D Rakić
Journal:  Sensors (Basel)       Date:  2016-09-01       Impact factor: 3.576

  2 in total

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