Literature DB >> 14674694

Human aurora-B binds to a proteasome alpha-subunit HC8 and undergoes degradation in a proteasome-dependent manner.

Fengjue Shu1, Shuguang Guo, Yongjun Dang, Meiyan Qi, Guangjin Zhou, Zekun Guo, Ying Zhang, Chaoqun Wu, Shouyuan Zhao, Long Yu.   

Abstract

Human Aurora/Ipl1-related kinase 2 (Aurora-B) is a key regulator of mitosis. Here human proteasome alpha-subunit C8 (HC8) was identified to interact with the Aurora-B by yeast two-hybrid screen. This finding was confirmed by GST pull-down assays and immunoprecipitation experiments. The Aurora-B protein level increased in HeLa cells cultured with proteasome inhibitor ALLN. Our data suggest that Aurora-B might undergo degradation by binding to HC8 in a proteasome-dependent manner during mitosis.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 14674694     DOI： 10.1023/a:1027317014159

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  29 in total

Review 1.  Ubiquitin-mediated proteolysis: biological regulation via destruction.

Authors:  A Ciechanover; A Orian; A L Schwartz
Journal:  Bioessays       Date:  2000-05       Impact factor: 4.345

Review 2.  Getting in and out of the proteasome.

Authors:  M H Glickman
Journal:  Semin Cell Dev Biol       Date:  2000-06       Impact factor: 7.727

Review 3.  Mitotic kinases as regulators of cell division and its checkpoints.

Authors:  E A Nigg
Journal:  Nat Rev Mol Cell Biol       Date:  2001-01       Impact factor: 94.444

4.  The human proteasomal subunit HsC8 induces ring formation of other alpha-type subunits.

Authors:  W L Gerards; W W de Jong; H Bloemendal; W Boelens
Journal:  J Mol Biol       Date:  1998-01-09       Impact factor: 5.469

5.  Assignment of STK6 to human chromosome 20q13.2-->q13.3 and a pseudogene STK6P to 1q41-->q42.

Authors:  M Kimura; Y Matsuda; T Eki; T Yoshioka; K Okumura; F Hanaoka; Y Okano
Journal:  Cytogenet Cell Genet       Date:  1997

6.  Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1.

Authors:  M Kimura; S Kotani; T Hattori; N Sumi; T Yoshioka; K Todokoro; Y Okano
Journal:  J Biol Chem       Date:  1997-05-23       Impact factor: 5.157

7.  Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast.

Authors:  T Tanaka; M Kimura; K Matsunaga; D Fukada; H Mori; Y Okano
Journal:  Cancer Res       Date:  1999-05-01       Impact factor: 12.701

Review 8.  The 26S proteasome: ubiquitin-mediated proteolysis in the tunnel.

Authors:  A L Kierszenbaum
Journal:  Mol Reprod Dev       Date:  2000-10       Impact factor: 2.609

9.  Degradation of human Aurora-A protein kinase is mediated by hCdh1.

Authors:  Sei ichi Taguchi; Kei Honda; Kazumitsu Sugiura; Akio Yamaguchi; Koichi Furukawa; Takeshi Urano
Journal:  FEBS Lett       Date:  2002-05-22       Impact factor: 4.124

10.  Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis.

Authors:  R Giet; D M Glover
Journal:  J Cell Biol       Date:  2001-02-19       Impact factor: 10.539
View more
  7 in total

1.  Protein Interaction between Ameloblastin and Proteasome Subunit α Type 3 Can Facilitate Redistribution of Ameloblastin Domains within Forming Enamel.

Authors:  Shuhui Geng; Shane N White; Michael L Paine; Malcolm L Snead
Journal:  J Biol Chem       Date:  2015-06-12       Impact factor: 5.157

2.  Plasminogen activator inhibitor type 1 interacts with alpha3 subunit of proteasome and modulates its activity.

Authors:  Joanna Boncela; Patrycja Przygodzka; Izabela Papiewska-Pajak; Elzbieta Wyroba; Magdalena Osinska; Czeslaw S Cierniewski
Journal:  J Biol Chem       Date:  2010-12-06       Impact factor: 5.157

3.  Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1.

Authors:  Ping Yi; Qin Feng; Larbi Amazit; David M Lonard; Sophia Y Tsai; Ming-Jer Tsai; Bert W O'Malley
Journal:  Mol Cell       Date:  2008-02-29       Impact factor: 17.970

Review 4.  The aurora kinases in cell cycle and leukemia.

Authors:  B Goldenson; J D Crispino
Journal:  Oncogene       Date:  2014-03-17       Impact factor: 9.867

Review 5.  Proteins directly interacting with mammalian 20S proteasomal subunits and ubiquitin-independent proteasomal degradation.

Authors:  Raúl Sánchez-Lanzas; José G Castaño
Journal:  Biomolecules       Date:  2014-12-19

Review 6.  A new aurora in anaplastic thyroid cancer therapy.

Authors:  Enke Baldini; Massimino D'Armiento; Salvatore Ulisse
Journal:  Int J Endocrinol       Date:  2014-07-01       Impact factor: 3.257

7.  MasterPATH: network analysis of functional genomics screening data.

Authors:  Natalia Rubanova; Guillaume Pinna; Jeremie Kropp; Anna Campalans; Juan Pablo Radicella; Anna Polesskaya; Annick Harel-Bellan; Nadya Morozova
Journal:  BMC Genomics       Date:  2020-09-14       Impact factor: 3.969
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.