Literature DB >> 14670724

Structure of the core-oligosaccharide with a characteristic D-glycero-alpha-D-talo-oct-2-ulosylonate-(2-->4)-3-deoxy-D-manno-oct-2-ulosonate [alpha-Ko-(2-->4)-Kdo] disaccharide in the lipopolysaccharide from Burkholderia cepacia.

Yasunori Isshiki1, Ulrich Zähringer, Kazuyoshi Kawahara.   

Abstract

The core oligosaccharide in the lipopolysaccharide (LPS) of Burkholderia cepacia GIFU 645(T) was investigated. After mild acid hydrolysis of the LPS, a heptasaccharide was isolated and identified by chemical analyses, GLC-MS, FABMS, and NMR spectroscopy as follows: [carbohydrate structure: see text] where L-alpha-D-Hep stands for L-glycero-alpha-D-manno-heptose, Ko for D-glycero-D-talo-oct-2-ulosonic acid, and Kdo for 3-deoxy-D-manno-oct-2-ulosonic acid.

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Year:  2003        PMID： 14670724     DOI： 10.1016/j.carres.2003.07.005

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  8 in total

1.  A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability.

Authors:  Ximena P Ortega; Silvia T Cardona; Alan R Brown; Slade A Loutet; Ronald S Flannagan; Dominic J Campopiano; John R W Govan; Miguel A Valvano
Journal:  J Bacteriol       Date:  2007-03-02       Impact factor: 3.490

2.  Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It.

Authors:  Helen I Zgurskaya; Cesar A Löpez; S Gnanakaran
Journal:  ACS Infect Dis       Date:  2015       Impact factor: 5.084

3.  Dioxygenases in Burkholderia ambifaria and Yersinia pestis that hydroxylate the outer Kdo unit of lipopolysaccharide.

Authors:  Hak Suk Chung; Christian R H Raetz
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-22       Impact factor: 11.205

4.  Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.

Authors:  Ximena Ortega; Tracey A Hunt; Slade Loutet; Arlene D Vinion-Dubiel; Anup Datta; Biswa Choudhury; Joanna B Goldberg; Russell Carlson; Miguel A Valvano
Journal:  J Bacteriol       Date:  2005-02       Impact factor: 3.490

5.  A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo.

Authors:  Slade A Loutet; Ronald S Flannagan; Cora Kooi; Pamela A Sokol; Miguel A Valvano
Journal:  J Bacteriol       Date:  2006-03       Impact factor: 3.490

6.  Kdo hydroxylase is an inner core assembly enzyme in the Ko-containing lipopolysaccharide biosynthesis.

Authors:  Hak Suk Chung; Eun Gyeong Yang; Dohyeon Hwang; Ji Eun Lee; Ziqiang Guan; Christian R H Raetz
Journal:  Biochem Biophys Res Commun       Date:  2014-09-06       Impact factor: 3.575

7.  Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B.

Authors:  Ximena Ortega; Alba Silipo; M Soledad Saldías; Christa C Bates; Antonio Molinaro; Miguel A Valvano
Journal:  J Biol Chem       Date:  2009-06-12       Impact factor: 5.157

Review 8.  Variation, Modification and Engineering of Lipid A in Endotoxin of Gram-Negative Bacteria.

Authors:  Kazuyoshi Kawahara
Journal:  Int J Mol Sci       Date:  2021-02-25       Impact factor: 5.923
  8 in total

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