| Literature DB >> 14670453 |
Abstract
A deeper understanding of the mechanisms that determine viral evolution in the context of an adaptive immune system is vital for the development of efficient strategies to defeat viral infections. The problem of describing these mechanisms is discussed using the concept of quasispecies. Conditions for both an optimal immune response and for highest viral viability are derived from theoretical models and are supported by empirical data.Entities:
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Year: 2003 PMID： 14670453 DOI： 10.1016/j.micinf.2003.10.001
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700