Literature DB >> 14669248

Cytotoxicity and antimicrobial activity of goniothalamin isolated from Bryonopsis laciniosa.

M Ashik Mosaddik1, M Ekramul Haque.   

Abstract

The cytotoxicity and antimicrobial activity of goniothalamin isolated from Bryonopsis laciniosa was investigated. Goniothalamin showed potent cytotoxicity with LC50 values (5.03 microg/mL) comparable with the reference standard agent, gallic acid. It also showed weak antibacterial and significant antifungal activity against a wide range of gram positive and gram negative bacteria and fungi. The antibacterial (minimum inhibitory concentration) effect against Bacillus cereus and Shigella shiga was found to be 64 microg/mL. Copyright 2003 John Wiley & Sons, Ltd.

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Year:  2003        PMID： 14669248     DOI： 10.1002/ptr.1303

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  8 in total

1.  Convenient synthesis of benzothiazinoisoindol-11-ones and benzoindenothiazin-11-ones, and antimicrobial testing thereof.

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Journal:  Mol Divers       Date:  2022-08-03       Impact factor: 3.364

2.  Mechanism of apoptosis induction associated with ERK1/2 upregulation via goniothalamin in melanoma cells.

Authors:  Suphakorn Tangchirakhaphan; Sukanda Innajak; Sirinun Nilwarangkoon; Nudjaree Tanjapatkul; Wilawan Mahabusrakum; Ramida Watanapokasin
Journal:  Exp Ther Med       Date:  2018-01-17       Impact factor: 2.447

3.  Antibacterial, antifungal and cytotoxic activities of amblyone isolated from Amorphophallus campanulatus.

Authors:  Alam Khan; Moizur Rahman; M S Islam
Journal:  Indian J Pharmacol       Date:  2008-01       Impact factor: 1.200

4.  Anti-diabetic effects of ethanol extract of Bryonia laciniosa seeds and its saponins rich fraction in neonatally streptozotocin-induced diabetic rats.

Authors:  Sandip B Patel; Devdas Santani; Veena Patel; Mamta Shah
Journal:  Pharmacognosy Res       Date:  2015 Jan-Mar

Review 5.  CRM1 Inhibitors for Antiviral Therapy.

Authors:  Cynthia Mathew; Reena Ghildyal
Journal:  Front Microbiol       Date:  2017-06-28       Impact factor: 5.640

6.  Selected α-pyrones from the plants Cryptocarya novoguineensis (Lauraceae) and Piper methysticum (Piperaceae) with activity against Haemonchus contortus in vitro.

Authors:  H M P Dilrukshi Herath; Sarah Preston; Abdul Jabbar; Jose Garcia-Bustos; Russell S Addison; Sasha Hayes; Topul Rali; Tao Wang; Anson V Koehler; Bill C H Chang; Andreas Hofmann; Rohan A Davis; Robin B Gasser
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2019-01-04       Impact factor: 4.077

7.  Anti-hyperglycemic and Anti-hyperlipidemic Effects of Bryonia Laciniosa Seed Extract and its Saponin Fraction in Streptozotocin-induced Diabetes in Rats.

Authors:  Sb Patel; D Santani; Mb Shah; Vs Patel
Journal:  J Young Pharm       Date:  2012-07

8.  Interaction between goniothalamin and peroxisomal multifunctional enzyme type 2 triggering endoplasmic reticulum stress.

Authors:  Thanet Sophonnithiprasert; Ornjira Aruksakunwong; Etsu Tashiro; Yasumitsu Kondoh; Makoto Muroi; Hiroyuki Osada; Masaya Imoto; Ramida Watanapokasin
Journal:  Heliyon       Date:  2020-10-15
  8 in total

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