OBJECTIVE: To compare the immediate effects of different training interventions on gait parameters in patients with early Parkinson's disease (PD). DESIGN: Randomized, multiple intervention crossover pilot study. SETTING: A rehabilitation center for adult persons with neurologic disorders. PARTICIPANTS: Seventeen patients with early PD (Hoehn and Yahr stages I through III) and gait disturbances. INTERVENTION: Patients were randomly assigned to varying sequences of the following interventions over 4 consecutive days: structured speed-dependent treadmill training (STT), limited progressive treadmill training (LTT), conventional gait training (CGT), and a control intervention. MAIN OUTCOME MEASURES: Basic gait parameters (overground walking speed and stride length at self-adapted speeds) and parameters of gait analysis based on vertical ground reaction forces. RESULTS:STT and LTT improved all basic gait parameters and the double stance duration compared with preintervention values (P<.05). No changes were found after CGT and the control intervention (P<.05). Significantly higher gains were observed in all basic gait parameters after STT and LTT when compared with CGT and the control intervention (P<.05). Additionally, a greater reduction of double stance duration was found after STT than after the control intervention (P<.001). No significant differences in gains were observed between STT and LTT, or between CGT and the control intervention, in all gait parameters. CONCLUSION: The main disturbances of gait in PD, namely, speed and stride length, can be improved through a single intervention of STT or LTT, but not through CGT and the control intervention.
RCT Entities:
OBJECTIVE: To compare the immediate effects of different training interventions on gait parameters in patients with early Parkinson's disease (PD). DESIGN: Randomized, multiple intervention crossover pilot study. SETTING: A rehabilitation center for adult persons with neurologic disorders. PARTICIPANTS: Seventeen patients with early PD (Hoehn and Yahr stages I through III) and gait disturbances. INTERVENTION: Patients were randomly assigned to varying sequences of the following interventions over 4 consecutive days: structured speed-dependent treadmill training (STT), limited progressive treadmill training (LTT), conventional gait training (CGT), and a control intervention. MAIN OUTCOME MEASURES: Basic gait parameters (overground walking speed and stride length at self-adapted speeds) and parameters of gait analysis based on vertical ground reaction forces. RESULTS:STT and LTT improved all basic gait parameters and the double stance duration compared with preintervention values (P<.05). No changes were found after CGT and the control intervention (P<.05). Significantly higher gains were observed in all basic gait parameters after STT and LTT when compared with CGT and the control intervention (P<.05). Additionally, a greater reduction of double stance duration was found after STT than after the control intervention (P<.001). No significant differences in gains were observed between STT and LTT, or between CGT and the control intervention, in all gait parameters. CONCLUSION: The main disturbances of gait in PD, namely, speed and stride length, can be improved through a single intervention of STT or LTT, but not through CGT and the control intervention.
Authors: Beth E Fisher; Allan D Wu; George J Salem; Jooeun Song; Chien-Ho Janice Lin; Jeanine Yip; Steven Cen; James Gordon; Michael Jakowec; Giselle Petzinger Journal: Arch Phys Med Rehabil Date: 2008-06-13 Impact factor: 3.966
Authors: Giselle M Petzinger; Beth E Fisher; Garnik Akopian; Daniel P Holschneider; Ruth Wood; John P Walsh; Brett Lund; Charles Meshul; Marta Vuckovic; Michael W Jakowec Journal: Neurodegener Dis Manag Date: 2011-04-01
Authors: Crystal D Batson; Rachel A Brady; Brian T Peters; Robert J Ploutz-Snyder; Ajitkumar P Mulavara; Helen S Cohen; Jacob J Bloomberg Journal: Exp Brain Res Date: 2011-02-25 Impact factor: 1.972
Authors: Claire L Tomlinson; Clare P Herd; Carl E Clarke; Charmaine Meek; Smitaa Patel; Rebecca Stowe; Katherine H O Deane; Laila Shah; Catherine M Sackley; Keith Wheatley; Natalie Ives Journal: Cochrane Database Syst Rev Date: 2014-06-17