| Literature DB >> 1466804 |
Abstract
In the past year, our understanding of the mechanisms that regulate isotype switching has significantly progressed. Activation of germ line transcription by isotype-specific cytokines is emerging as a crucial mechanism for increasing the accessibility of a particular switch region, and targeting switch recombination.Mesh:
Substances:
Year: 1992 PMID: 1466804 DOI: 10.1016/0952-7915(92)90064-l
Source DB: PubMed Journal: Curr Opin Immunol ISSN: 0952-7915 Impact factor: 7.486