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Literature DB >> 1466803

Role of type 1 and type 2 T helper cells in allergic diseases.

M L Kapsenberg¹, H M Jansen, J D Bos, E A Wierenga.

Abstract

Various characteristics of atopic allergic disorders seem to be causally related with the activation of allergen-specific T helper lymphocytes with a type 2 cytokine secretion profile, including high levels of interleukin-4 and interleukin-5. These cytokines are responsible for the occurrence of elevated levels of serum allergen-specific IgE and eosinophilia and play an important role in local inflammatory reactions.

Entities: Disease Gene

Mesh：

Substances：
Immunoglobulin E

Year: 1992 PMID： 1466803 DOI： 10.1016/0952-7915(92)90063-k

Source DB: PubMed Journal: Curr Opin Immunol ISSN： 0952-7915 Impact factor: 7.486

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Cited

13 in total

1. Immunostimulatory oligodeoxynucleotide from Bifidobacterium longum suppresses Th2 immune responses in a murine model.

Authors: N Takahashi; H Kitazawa; N Iwabuchi; J Z Xiao; K Miyaji; K Iwatsuki; T Saito
Journal: Clin Exp Immunol Date: 2006-07 Impact factor: 4.330

Review 2. Immunopathogenesis of juvenile rheumatoid arthritis: role of T cells and MHC.

Authors: L I Sakkas; C D Platsoucas
Journal: Immunol Res Date: 1995 Impact factor: 2.829

Review 3. The role of allergy in sinus disease. Children and adults.

Authors: Z Pelikan
Journal: Clin Rev Allergy Immunol Date: 1998 Spring-Summer Impact factor: 8.667

4. Association between specific timothy grass antigens and changes in TH1- and TH2-cell responses following specific immunotherapy.

Authors: Véronique Schulten; Victoria Tripple; John Sidney; Jason Greenbaum; April Frazier; Rafeul Alam; David Broide; Bjoern Peters; Alessandro Sette
Journal: J Allergy Clin Immunol Date: 2014-07-16 Impact factor: 10.793

5. Histamine inhibits the production of interleukin-12 through interaction with H2 receptors.

Authors: T C van der Pouw Kraan; A Snijders; L C Boeije; E R de Groot; A E Alewijnse; R Leurs; L A Aarden
Journal: J Clin Invest Date: 1998-11-15 Impact factor: 14.808

6. Attenuation of Th1 effector cell responses and susceptibility to experimental allergic encephalomyelitis in histamine H2 receptor knockout mice is due to dysregulation of cytokine production by antigen-presenting cells.

Authors: Cory Teuscher; Matthew E Poynter; Halina Offner; Alex Zamora; Takeshi Watanabe; Parley D Fillmore; James F Zachary; Elizabeth P Blankenhorn
Journal: Am J Pathol Date: 2004-03 Impact factor: 4.307

Role of type 1 and type 2 T helper cells in allergic diseases.

1. Immunostimulatory oligodeoxynucleotide from Bifidobacterium longum suppresses Th2 immune responses in a murine model.

Review 2. Immunopathogenesis of juvenile rheumatoid arthritis: role of T cells and MHC.

Review 3. The role of allergy in sinus disease. Children and adults.

4. Association between specific timothy grass antigens and changes in TH1- and TH2-cell responses following specific immunotherapy.

5. Histamine inhibits the production of interleukin-12 through interaction with H2 receptors.

6. Attenuation of Th1 effector cell responses and susceptibility to experimental allergic encephalomyelitis in histamine H2 receptor knockout mice is due to dysregulation of cytokine production by antigen-presenting cells.

7. Allergen-specific subcutaneous immunotherapy in allergic asthma: immunologic mechanisms and improvement.

8. Pingchuan formula improves asthma via restoration of the Th17/Treg balance in a mouse model.

9. CryJ-LAMP DNA Vaccines for Japanese Red Cedar Allergy Induce Robust Th1-Type Immune Responses in Murine Model.

10. Nasal hyperreactivity and inflammation in allergic rhinitis.