Literature DB >> 14667501

Will mTOR inhibitors make it as cancer drugs?

Charles L Sawyers1.   

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Year:  2003        PMID: 14667501     DOI: 10.1016/s1535-6108(03)00275-7

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


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  71 in total

1.  Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells.

Authors:  Yewseok Suh; Farrukh Afaq; Naghma Khan; Jeremy J Johnson; Fatima H Khusro; Hasan Mukhtar
Journal:  Carcinogenesis       Date:  2010-06-08       Impact factor: 4.944

2.  High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.

Authors:  Paige Yellen; Mahesh Saqcena; Darin Salloum; Jiangnan Feng; Angela Preda; Limei Xu; Vanessa Rodrik-Outmezguine; David A Foster
Journal:  Cell Cycle       Date:  2011-11-15       Impact factor: 4.534

Review 3.  New molecular targets for treatment of lymphoma.

Authors:  Barbara Pro; Anas Younes
Journal:  Curr Oncol Rep       Date:  2004-09       Impact factor: 5.075

Review 4.  The potential role of mTOR inhibitors in the treatment of endocrine tumors.

Authors:  S Grozinsky-Glasberg; I Shimon
Journal:  J Endocrinol Invest       Date:  2010-05-05       Impact factor: 4.256

5.  Rapamycin with antiretroviral therapy in AIDS-associated Kaposi sarcoma: an AIDS Malignancy Consortium study.

Authors:  Susan E Krown; Debasmita Roy; Jeannette Y Lee; Bruce J Dezube; Erin G Reid; Raman Venkataramanan; Kelong Han; Ethel Cesarman; Dirk P Dittmer
Journal:  J Acquir Immune Defic Syndr       Date:  2012-04-15       Impact factor: 3.731

Review 6.  Signaling by target of rapamycin proteins in cell growth control.

Authors:  Ken Inoki; Hongjiao Ouyang; Yong Li; Kun-Liang Guan
Journal:  Microbiol Mol Biol Rev       Date:  2005-03       Impact factor: 11.056

7.  IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes.

Authors:  Michal Marzec; Xiaobin Liu; Monika Kasprzycka; Agnieszka Witkiewicz; Puthiyaveettil N Raghunath; Mouna El-Salem; Erle Robertson; Niels Odum; Mariusz A Wasik
Journal:  Blood       Date:  2007-11-19       Impact factor: 22.113

8.  Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia.

Authors:  Steven M Chan; Andrew P Weng; Robert Tibshirani; Jon C Aster; Paul J Utz
Journal:  Blood       Date:  2007-03-15       Impact factor: 22.113

9.  The effects of mTOR-Akt interactions on anti-apoptotic signaling in vascular endothelial cells.

Authors:  Olivier Dormond; Joren C Madsen; David M Briscoe
Journal:  J Biol Chem       Date:  2007-06-06       Impact factor: 5.157

10.  Intravesical delivery of rapamycin suppresses tumorigenesis in a mouse model of progressive bladder cancer.

Authors:  Catherine M Seager; Anna M Puzio-Kuter; Trushar Patel; Shalini Jain; Carlos Cordon-Cardo; James Mc Kiernan; Cory Abate-Shen
Journal:  Cancer Prev Res (Phila)       Date:  2009-12-01
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