Literature DB >> 1466750

A strategy to improve the efficacy of vaccination against tuberculosis and leprosy.

P A Bretscher1.   

Abstract

The pathogens responsible for leprosy, tuberculosis and the leishmaniases can induce different classes of immunity, but protection is provided only by a cell-mediated response. Here, Peter Bretscher proposes a strategy to achieve an immunological imprint that ensures a stable cell-mediated response upon natural infection.

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Year:  1992        PMID： 1466750     DOI： 10.1016/0167-5699(92)90168-7

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  18 in total

1.  T lymphocyte immunity in host defence against Chlamydia trachomatis and its implication for vaccine development.

Authors:  X Yang; R Brunham
Journal:  Can J Infect Dis       Date:  1998-03

2.  Activation of an interleukin-4 mRNA-producing population of peripheral blood mononuclear cells after infection with Mycobacterium bovis or vaccination with killed, but not live, BCG.

Authors:  S Hook; F Griffin; C Mackintosh; G Buchan
Journal:  Immunology       Date:  1996-06       Impact factor: 7.397

3.  Role of viral infections in the inception of childhood asthma and allergies.

Authors:  J M Grange; J L Stanford; G A Rook; P Wright
Journal:  Thorax       Date:  1995-06       Impact factor: 9.139

4.  Mycobacterial dose defines the Th1/Th2 nature of the immune response independently of whether immunization is administered by the intravenous, subcutaneous, or intradermal route.

Authors:  C A Power; G Wei; P A Bretscher
Journal:  Infect Immun       Date:  1998-12       Impact factor: 3.441

Review 5.  Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases.

Authors:  D R Lucey; M Clerici; G M Shearer
Journal:  Clin Microbiol Rev       Date:  1996-10       Impact factor: 26.132

6.  Hansen's Disease--a time for cautious optimism.

Authors:  R A Miller
Journal:  West J Med       Date:  1993-06

7.  Tuberculosis and HIV: light after darkness.

Authors:  J M Grange; J L Stanford; G Rook; P Onyebujoh; P A Bretscher
Journal:  Thorax       Date:  1994-06       Impact factor: 9.139

8.  Pathogenesis of tuberculosis in mice exposed to low and high doses of an environmental mycobacterial saprophyte before infection.

Authors:  R Hernandez-Pando; L Pavön; K Arriaga; H Orozco; V Madrid-Marina; G Rook
Journal:  Infect Immun       Date:  1997-08       Impact factor: 3.441

9.  Dynamics of gamma interferon, interleukin-12 (IL-12), IL-10, and transforming growth factor beta mRNA expression in primary Mycobacterium bovis BCG infection in guinea pigs measured by a real-time fluorogenic reverse transcription-PCR assay.

Authors:  Mamoru Kawahara; Tadashi Nakasone; Mitsuo Honda
Journal:  Infect Immun       Date:  2002-12       Impact factor: 3.441

10.  Distinct H-2 complex control of mortality, and immune responses to tuberculosis infection in virgin and BCG-vaccinated mice.

Authors:  A S Apt; V G Avdienko; B V Nikonenko; I B Kramnik; A M Moroz; E Skamene
Journal:  Clin Exp Immunol       Date:  1993-11       Impact factor: 4.330
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