Literature DB >> 14666378

Reactivation of Epstein-Barr virus in patients with systemic lupus erythematosus.

Mary L Huggins1, Ian Todd, Richard J Powell.   

Abstract

A link between Epstein-Barr Virus (EBV) and systemic lupus erythematosus (SLE) has been suggested. However, recent advances in molecular technology now permit more detailed analysis. Sera from SLE patients were tested for antibodies to several EBV antigens and had a significantly higher prevalence of immunoglobulin G antibodies against EBV early antigens than in normal or disease controls. This suggests that recent EBV infection or virus reactivation was occurring in these patients.

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Year:  2003        PMID: 14666378     DOI: 10.1007/s00296-003-0420-2

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN: 0172-8172            Impact factor:   2.631


  8 in total

1.  Epstein-Barr virus infection may be an environmental risk factor for systemic lupus erythematosus in children and teenagers.

Authors:  J B Harley; J A James
Journal:  Arthritis Rheum       Date:  1999-08

2.  B-cell-derived IL-10: production and function.

Authors:  N Burdin; F Rousset; J Banchereau
Journal:  Methods       Date:  1997-01       Impact factor: 3.608

3.  Raised antibody titres to E.B. virus in systemic lupus erythematosus.

Authors:  A S Evans; N F Rothfield; J C Niederman
Journal:  Lancet       Date:  1971-01-23       Impact factor: 79.321

4.  Quantitative and qualitative analysis of the balance between type 1 and type 2 cytokine-producing CD8(-) and CD8(+) T cells in systemic lupus erythematosus.

Authors:  M R Amel-Kashipaz; M L Huggins; P Lanyon; A Robins; I Todd; R J Powell
Journal:  J Autoimmun       Date:  2001-09       Impact factor: 7.094

5.  Epstein-Barr virus burden in adolescents with systemic lupus erythematosus.

Authors:  B Z Katz; B Salimi; S Kim; P Nsiah-Kumi; L Wagner-Weiner
Journal:  Pediatr Infect Dis J       Date:  2001-02       Impact factor: 2.129

6.  An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus.

Authors:  J A James; K M Kaufman; A D Farris; E Taylor-Albert; T J Lehman; J B Harley
Journal:  J Clin Invest       Date:  1997-12-15       Impact factor: 14.808

7.  Paralysis of B7 co-stimulation through the effect of viral IL-10 on T cells as a mechanism of local tolerance induction.

Authors:  A Müller; L Schmitt; M Raftery; G Schönrich
Journal:  Eur J Immunol       Date:  1998-11       Impact factor: 5.532

8.  Assessment of Be1 and Be2 cells in systemic lupus erythematosus indicates elevated interleukin-10 producing CD5+ B cells.

Authors:  M R Amel Kashipaz; M L Huggins; P Lanyon; A Robins; R J Powell; I Todd
Journal:  Lupus       Date:  2003       Impact factor: 2.911

  8 in total
  13 in total

1.  Phantom cytomegalovirus infection in vasculitis patients: what it means and what to do.

Authors:  Konstantinos H Katsanos; Aggeliki Kostoula; Konstantinos P Katopodis; Kostas C Siamopoulos
Journal:  Rheumatol Int       Date:  2004-10-16       Impact factor: 2.631

2.  Serologic response to Epstein-Barr virus antigens in patients with systemic lupus erythematosus: a controlled study.

Authors:  Bahar Artım Esen; Gülden Yılmaz; Sami Uzun; Melda Ozdamar; Alper Aksözek; Sevil Kamalı; Salih Türkoğlu; Ahmet Gül; Lale Ocal; Orhan Aral; Murat Inanç
Journal:  Rheumatol Int       Date:  2010-07-27       Impact factor: 2.631

Review 3.  Epstein-Barr virus and systemic lupus erythematosus.

Authors:  Anette Holck Draborg; Karen Duus; Gunnar Houen
Journal:  Clin Dev Immunol       Date:  2012-07-03

4.  Antibodies to early EBV, CMV, and HHV6 antigens in systemic lupus erythematosus patients.

Authors:  N S Rasmussen; A H Draborg; C T Nielsen; S Jacobsen; G Houen
Journal:  Scand J Rheumatol       Date:  2015-01-06       Impact factor: 3.641

Review 5.  Systematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and systemic lupus erythematosus.

Authors:  Peter Hanlon; Alison Avenell; Lorna Aucott; Mark A Vickers
Journal:  Arthritis Res Ther       Date:  2014-01-06       Impact factor: 5.156

6.  Reduced response to Epstein-Barr virus antigens by T-cells in systemic lupus erythematosus patients.

Authors:  Anette Holck Draborg; Søren Jacobsen; Marie Westergaard; Shila Mortensen; Janni Lisander Larsen; Gunnar Houen; Karen Duus
Journal:  Lupus Sci Med       Date:  2014-04-01

7.  Elevated Concentrations of Serum Immunoglobulin Free Light Chains in Systemic Lupus Erythematosus Patients in Relation to Disease Activity, Inflammatory Status, B Cell Activity and Epstein-Barr Virus Antibodies.

Authors:  Anette H Draborg; Magnus C Lydolph; Marie Westergaard; Severin Olesen Larsen; Christoffer T Nielsen; Karen Duus; Søren Jacobsen; Gunnar Houen
Journal:  PLoS One       Date:  2015-09-24       Impact factor: 3.240

Review 8.  Epstein-Barr virus in systemic autoimmune diseases.

Authors:  Anette Holck Draborg; Karen Duus; Gunnar Houen
Journal:  Clin Dev Immunol       Date:  2013-08-24

9.  Impaired Cytokine Responses to Epstein-Barr Virus Antigens in Systemic Lupus Erythematosus Patients.

Authors:  Anette Holck Draborg; Noreen Sandhu; Nanna Larsen; Janni Lisander Larsen; Søren Jacobsen; Gunnar Houen
Journal:  J Immunol Res       Date:  2016-03-27       Impact factor: 4.818

10.  Strong viral associations with SLE among Filipinos.

Authors:  Evan S Vista; Michael H Weisman; Mariko L Ishimori; Hua Chen; Rebecka L Bourn; Ben F Bruner; Laniyati Hamijoyo; Robelle D Tanangunan; Noga J Gal; Julie M Robertson; John B Harley; Joel M Guthridge; Sandra V Navarra; Judith A James
Journal:  Lupus Sci Med       Date:  2017-07-28
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