| Literature DB >> 14664923 |
Emmanuelle Cousin1, Didier Hannequin, Sandrine Macé, Bruno Dubois, Sylvain Ricard, Emmanuelle Génin, Christophe Brun, Céline Chansac, Laurent Pradier, Thierry Frebourg, Alexis Brice, Dominique Campion, Jean-François Deleuze.
Abstract
Polymorphisms in the Nicastrin (NCSTN) gene have recently been associated with familial early-onset Alzheimer's disease (AD). The authors genotyped four NCTSN polymorphisms in a large cohort of 489 AD cases (including 158 sporadic early-onset AD cases and 95 familial early-onset AD cases) and 386 controls but failed to replicate the association between NCSTN haplotype B and AD.Entities:
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Year: 2003 PMID: 14664923 DOI: 10.1016/s0304-3940(03)01105-4
Source DB: PubMed Journal: Neurosci Lett ISSN: 0304-3940 Impact factor: 3.046