Literature DB >> 14664515

Antifungal clerodane diterpenes from Macaranga monandra (L) Muell. et Arg. (Euphorbiaceae).

Martin A Salah1, Erdal Bedir, Ngeh J Toyang, Ikhlas A Khan, M Dewayne Harries, David E Wedge.   

Abstract

Hexane and ethyl acetate phases of the methanol extract of Macaranga monandra showed fungal growth inhibition of Colletotrichum acutatum, C. fragariae and C. gloeosporioides, Fusarium oxysporum, Botrytis cinerea, Phomopsis obscurans, and P. viticola. Bioassay-guided fractionation led to the isolation of two active clerodane-type diterpenes that were elucidated by spectroscopic methods (1D-, 2D-NMR, and MS) as kolavenic acid and 2-oxo-kolavenic acid. A 96-well microbioassay revealed that kolavenic acid and 2-oxo-kolavenic acid produced moderate growth inhibition in Phomopsis viticola and Botrytis cinerea.

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Year:  2003        PMID： 14664515     DOI： 10.1021/jf034682w

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN： 0021-8561            Impact factor:   5.279


  6 in total

1.  Antiproliferative prenylated stilbenes and flavonoids from Macaranga alnifolia from the Madagascar rainforest.

Authors:  Brent J Yoder; Shugeng Cao; Andrew Norris; James S Miller; Fidy Ratovoson; Jeremi Razafitsalama; Rabodo Andriantsiferana; Vincent E Rasamison; David G I Kingston
Journal:  J Nat Prod       Date:  2007-02-28       Impact factor: 4.050

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Journal:  Int J Mol Sci       Date:  2017-06-17       Impact factor: 5.923

3.  Volatile unsaturated hydrocarbons emitted by seedlings of Brassica species provide host location cues to Bagrada hilaris.

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Journal:  PLoS One       Date:  2018-12-27       Impact factor: 3.240

4.  Antiamoebic activity of plant-based natural products and their conjugated silver nanoparticles against Acanthamoeba castellanii (ATCC 50492).

Authors:  Areeba Anwar; Elaine Lim Siew Ting; Ayaz Anwar; Noor Ul Ain; Shaheen Faizi; Muhammad Raza Shah; Naveed Ahmed Khan; Ruqaiyyah Siddiqui
Journal:  AMB Express       Date:  2020-02-03       Impact factor: 3.298

5.  In vitro antifungal activity of the diterpenoid 7 alpha-hydroxy-8(17)-labden-15-oic acid and its derivatives against Botrytis cinerea.

Authors:  Leonora Mendoza; Pamela Espinoza; Alejandro Urzua; Marcela Vivanco; Milena Cotoras
Journal:  Molecules       Date:  2009-05-26       Impact factor: 4.411

Review 6.  13C-NMR data of diterpenes isolated from Aristolochia Species.

Authors:  Alison Geraldo Pacheco; Patrícia Machado de Oliveira; Dorila Piló-Veloso; Antônio Flávio de Carvalho Alcântara
Journal:  Molecules       Date:  2009-03-23       Impact factor: 4.411
  6 in total

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