Triggers for use, optimal dosing, and problems associated with red cell transfusions.

The administration of RBC components can dramatically improve tissue oxygenation in small animals with symptomatic anemia and can be life saving. This therapy is not without risk, however. Careful consideration of the transfusion trigger, appropriate screening of the donor and recipient, and selection of the optimal RBC component and dose on an individual patient basis can help to limit the occurrence of adverse transfusion-related events. Appropriate component administration techniques, careful monitoring of recipients for the development of transfusion reactions, and prompt recognition and treatment of transfusion reactions are also essential in assuring safe transfusion practice.