Literature DB >> 14663542

Proton MR spectroscopy in neuroborreliosis: a preliminary study.

A Ustymowicz1, E Tarasów, J Zajkowska, J Walecki, T Hermanowska-Szpakowicz.   

Abstract

We report results of a magnetic resonance spectroscopy (MRS) study in 12 patients with neuroborreliosis. We used a PRESS sequence, placing an 8 cm3 voxel in normal-appearing white matter of the frontal lobe. Peaks indicating N-acetylaspartate (NAA), choline (Cho), creatine (Cr), myo-inositol (mI), lipids (Lip) and lactate (Lac) were identified and ratios of NAA/Cr, Cho/Cr, mI/Cr, Lip/Cr, Lac/Cr calculated. Significant increases in Cho/Cr and Lip/Cr were noted. No abnormality was found in mean NAA/Cr and Lac/Cr, but in four patients there was a decreased NAA peak; mI/Cr ratio was slightly increased. Although the spectroscopic profile in patients with neuroborreliosis seems to be nonspecific, MRS might be useful for assessing tissue damage of the central nervous system.

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Year:  2003        PMID： 14663542     DOI： 10.1007/s00234-002-0851-6

Source DB:  PubMed          Journal:  Neuroradiology        ISSN： 0028-3940            Impact factor:   2.804


  25 in total

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Journal:  AJNR Am J Neuroradiol       Date:  1998-01       Impact factor: 3.825

9.  Stages and syndromes of neuroborreliosis.

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10.  Brain choline-containing compounds are elevated in HIV-positive patients before the onset of AIDS dementia complex: A proton magnetic resonance spectroscopic study.

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  1 in total

1.  Neuronal loss or dysfunction in patients with early Lyme neuroborreliosis: a proton magnetic resonance spectroscopy study of the brain.

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Journal:  J Neurol       Date:  2019-05-10       Impact factor: 4.849
  1 in total

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